iPTMnet Report Q15013 MAD2L1BP

Protein Information

Cytoscape View

UniProt AC / UniProt ID	Q15013 / MD2BP_HUMAN
Protein Name	MAD2L1-binding protein
Gene Name	Name: MAD2L1BP Synonyms:CMT2,KIAA0110;
Organism	Homo sapiens (Human)

PRO ID	PR:Q15013 DAG View
PRO Name	MAD2L1-binding protein (human)
Definition	A MAD2L1-binding protein that is encoded in the genome of human.
Short Label	hMAD2L1BP
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q15013 (MAD2L1BP) as Substrate

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S23	Phosphorylation		score2	phospho.ELM PhosphoSitePlus	22067460
	S29	Phosphorylation		score2	phospho.ELM PhosphoSitePlus	17525332
	T36	Phosphorylation		score1	PhosphoSitePlus
	S37	Phosphorylation		score2	phospho.ELM PhosphoSitePlus	22067460, 18669648
	S38	Phosphorylation		score1	PhosphoSitePlus
	T39	Phosphorylation		score2	phospho.ELM PhosphoSitePlus	22067460, 17525332
	S46	Phosphorylation		score2	phospho.ELM PhosphoSitePlus	22067460
	K78	Ubiquitination		score1	PhosphoSitePlus
	K95	Ubiquitination		score1	PhosphoSitePlus
	Y98	Phosphorylation		score1	PhosphoSitePlus
	K100	Ubiquitination		score1	PhosphoSitePlus
	S102	Phosphorylation	P53350 (PLK1)	score4	phospho.ELM PhosphoSitePlus Signor UniProt	22067460, 31118282, 23186163
	K110	Ubiquitination		score1	PhosphoSitePlus
	K229	Ubiquitination		score1	PhosphoSitePlus
	Y232	Phosphorylation		score1	PhosphoSitePlus
	S246	Phosphorylation		score1	PhosphoSitePlus
	S251	Phosphorylation		score1	PhosphoSitePlus

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S29	Phosphorylation		score0	HPRD	17525332
	S37	Phosphorylation		score0	HPRD	18669648
	T39	Phosphorylation		score0	HPRD	17525332

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S13	Phosphorylation		score1	PhosphoSitePlus
	S61	Phosphorylation		score0	HPRD	17525332
	S69	Phosphorylation		score0	HPRD	18669648
	T71	Phosphorylation		score0	HPRD	17525332

Proteoform PPIs

	Protein 1	Relation	Protein 2	Source	PMID
	PR:O60566 (hBUB1B)	Interaction	PR:Q15013 (hMAD2L1BP)	PRO
	PR:Q15013 (hMAD2L1BP)	Interaction		PRO	22566641

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
S23	F23	Biomuta		DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]