iPTMnet Report for Q15008 (PSMD6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15008 / PSMD6_HUMAN
Protein Name 26S proteasome non-ATPase regulatory subunit 6
Gene Name Name: PSMD6
Synonyms:KIAA0107,PFAAP4;
Organism Homo sapiens (Human)

PRO ID PR:Q15008
DAG View
PRO Name 26S proteasome non-ATPase regulatory subunit 6 (human)
Definition A 26S proteasome non-ATPase regulatory subunit 6 that is encoded in the genome of human.
Short Label hPSMD6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15008 (PSMD6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K13 Ubiquitination PhosphoSitePlus
R18 Methylation PhosphoSitePlus
S27 Phosphorylation IEDB 35494241
K82 Ubiquitination PhosphoSitePlus
K93 Ubiquitination PhosphoSitePlus
K107 Ubiquitination PhosphoSitePlus
K117 Acetylation PhosphoSitePlus
K117 Ubiquitination PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
K130 Ubiquitination PhosphoSitePlus
K165 Ubiquitination PhosphoSitePlus
S166 Phosphorylation PhosphoSitePlus
K181 Ubiquitination PhosphoSitePlus
C188 Methylation IEDB 31844290
Y222 Phosphorylation PhosphoSitePlus
Y225 Phosphorylation PhosphoSitePlus
S227 Phosphorylation PhosphoSitePlus
K242 Ubiquitination PhosphoSitePlus
C266 Methylation IEDB 31844290
K284 Ubiquitination PhosphoSitePlus
K349 Ubiquitination PhosphoSitePlus
S361 Phosphorylation PhosphoSitePlus
K362 Ubiquitination PhosphoSitePlus
Y366 Phosphorylation PhosphoSitePlus
T369 Phosphorylation PhosphoSitePlus
K371 Ubiquitination PhosphoSitePlus
K372 Ubiquitination PhosphoSitePlus
R379 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S361 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
K91 Ubiquitination PhosphoSitePlus
K95 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K93 N93 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
K117 N117 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
K117 R117 Biomuta DOID:363 / uterine cancer [ icgc ]
T369 P369 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
R379 I379 Biomuta DOID:3571 / liver cancer [ cosmic ]