iPTMnet Report for Q15007 (WTAP)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15007 / FL2D_HUMAN
Protein Name Pre-mRNA-splicing regulator WTAP
Gene Name Name: WTAP
Synonyms:KIAA0105;
Organism Homo sapiens (Human)

PRO ID PR:Q15007
DAG View
PRO Name pre-mRNA-splicing regulator WTAP (human)
Definition A pre-mRNA-splicing regulator WTAP that is encoded in the genome of human.
Short Label hWTAP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15007 (WTAP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
T2 Phosphorylation PhosphoSitePlus
K10 Ubiquitination PhosphoSitePlus
S14 Phosphorylation PhosphoSitePlus   UniProt 23186163
K19 Ubiquitination PhosphoSitePlus
K31 Ubiquitination PhosphoSitePlus
K43 Ubiquitination PhosphoSitePlus
Y44 Phosphorylation PhosphoSitePlus
S49 Phosphorylation PhosphoSitePlus
S58 Phosphorylation PhosphoSitePlus
K61 Ubiquitination PhosphoSitePlus
K63 Ubiquitination PhosphoSitePlus
S69 Phosphorylation PhosphoSitePlus
K83 Ubiquitination PhosphoSitePlus
K98 Ubiquitination PhosphoSitePlus
K125 Sumoylation PhosphoSitePlus
K125 Ubiquitination PhosphoSitePlus
K134 Ubiquitination PhosphoSitePlus
K146 Ubiquitination PhosphoSitePlus
T148 Phosphorylation PhosphoSitePlus
K191 Ubiquitination PhosphoSitePlus
S244 Phosphorylation PhosphoSitePlus
S267 Phosphorylation PhosphoSitePlus
C270 S-Nitrosylation dbSNO 26338901
T274 Phosphorylation PhosphoSitePlus
S288 Phosphorylation PhosphoSitePlus
S290 Phosphorylation PhosphoSitePlus
T298 Phosphorylation PhosphoSitePlus
T299 Phosphorylation PhosphoSitePlus
S305 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332
S306 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 15302935, 18669648, ...19690332, 20068231
S313 Phosphorylation PhosphoSitePlus
S314 Phosphorylation PhosphoSitePlus
S316 Phosphorylation PhosphoSitePlus
S317 Phosphorylation PhosphoSitePlus
S341 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P 18669648, 34312368
T343 Phosphorylation PhosphoSitePlus
S345 Phosphorylation PhosphoSitePlus
S348 Phosphorylation PhosphoSitePlus
S388 Phosphorylation PhosphoSitePlus   UniProt 20068231
Site PTM Type PTM Enzyme Score Source PMID
T2 Phosphorylation HPRD 20068231
S244 Phosphorylation HPRD 17525332, 18077418
S288 Phosphorylation HPRD 17081983, 20068231
T298 Phosphorylation HPRD 20068231
S305 Phosphorylation HPRD 18669648, 18491316, 17081983, ...20068231, 19664995
S306 Phosphorylation HPRD 19413330, 18491316, 17081983, ...19664994, 19664995, 18452278, 19651622, 18669648, 20068231
S341 Phosphorylation HPRD 18669648, 18452278
T343 Phosphorylation HPRD 18452278
S348 Phosphorylation HPRD 18452278
S388 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
T2 Phosphorylation HPRD 20068231
K146 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y44 * Biomuta DOID:1612 / breast cancer [ cosmic ]
T148 M148 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S244 C244 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ]
S305 P305 Biomuta DOID:4159 / skin cancer [ cosmic ]
S313 F313 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S314 C314 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T343 A343 Biomuta [ cosmic ]