iPTMnet Report for Q15006 (EMC2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15006 / EMC2_HUMAN
Protein Name ER membrane protein complex subunit 2
Gene Name Name: EMC2
Synonyms:KIAA0103;
Organism Homo sapiens (Human)

PRO ID PR:Q15006
DAG View
PRO Name ER membrane protein complex subunit 2 (human)
Definition An ER membrane protein complex subunit 2 that is encoded in the genome of human.
Short Label hEMC2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15006 (EMC2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378
R112 Methylation PhosphoSitePlus
T121 Phosphorylation PhosphoSitePlus
K136 Ubiquitination PhosphoSitePlus
C177 Methylation IEDB 31844290
T201 O-Glycosylation GlyGen 36240223, 28510447, 34229054
K220 Ubiquitination PhosphoSitePlus
K255 Acetylation PhosphoSitePlus   UniProt 19608861
K255 Ubiquitination PhosphoSitePlus
K276 Acetylation PhosphoSitePlus
K279 Acetylation PhosphoSitePlus
K283 Acetylation PhosphoSitePlus
S297 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R112 G112 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
T201 A201 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K283 N283 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]