iPTMnet Report for Q15004 (PCLAF)
Protein Information
UniProt AC / UniProt ID | Q15004 / PAF15_HUMAN |
Protein Name | PCNA-associated factor |
Gene Name | Name: PCLAF Synonyms:KIAA0101,NS5ATP9,PAF;ORFNames:L5; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q15004 |
PRO Name | PCNA-associated factor (human) |
Definition | A PCNA-associated factor that is encoded in the genome of human. |
Short Label | hPCLAF |
Category | organism-gene |
Q15004 (PCLAF) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T4 | Phosphorylation | score1 | PhosphoSitePlus | |||
K5 | Ubiquitination | score1 | PhosphoSitePlus | |||
S8 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
T12 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y13 | Phosphorylation | score1 | PhosphoSitePlus | |||
K15 | Methylation | score1 | PhosphoSitePlus | |||
K15 | Ubiquitination | score3 | PRO PhosphoSitePlus UniProt | 23000965 | ||
K24 | Acetylation | score1 | PhosphoSitePlus | |||
K24 | Ubiquitination | score3 | PRO PhosphoSitePlus UniProt | 23000965 | ||
S28 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
T30 | Phosphorylation | score1 | PhosphoSitePlus | |||
S31 | Phosphorylation | score3 | PhosphoSitePlus UniProt | 21628590 | ||
N34 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
S37 | Phosphorylation | score1 | PhosphoSitePlus | |||
C54 | Methylation | score1 | IEDB | 31844290 | ||
K60 | Ubiquitination | score1 | PhosphoSitePlus | |||
K63 | Ubiquitination | score1 | PhosphoSitePlus | |||
S72 | Phosphorylation | score4 | phospho.ELM PhosphoSitePlus UniProt | 21628590, 18669648, 23186163, ... | ||
S88 | Phosphorylation | score1 | PhosphoSitePlus | |||
K93 | Acetylation | score1 | PhosphoSitePlus | |||
K93 | Ubiquitination | score1 | PhosphoSitePlus | |||
K95 | Acetylation | score1 | PhosphoSitePlus | |||
T106 | Phosphorylation | score1 | PhosphoSitePlus |
Proteoforms
PRO ID (Short Label) | Sites | PTM Enzyme | Source | PMID | |
---|---|---|---|---|---|
PR:000048106 (hPCLAF/Ubiq:1) | ubK15,ubK24 | PRO |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
N34 | K34 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S72 | Y72 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
S72 | P72 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |