iPTMnet Report for Q15003 (NCAPH)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15003 / CND2_HUMAN
Protein Name Condensin complex subunit 2
Gene Name Name: NCAPH
Synonyms:BRRN,BRRN1,CAPH,KIAA0074;
Organism Homo sapiens (Human)

PRO ID PR:Q15003
DAG View
PRO Name condensin complex subunit 2 (human)
Definition A condensin complex subunit 2 that is encoded in the genome of human.
Short Label hNCAPH
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15003 (NCAPH) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Phosphorylation PRO
S15 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
S16 Phosphorylation phospho.ELM 18669648
S17 Phosphorylation phospho.ELM 18669648
R20 Methylation PhosphoSitePlus
S25 Phosphorylation PhosphoSitePlus   UniProt 20068231
S27 Phosphorylation PhosphoSitePlus
S28 Phosphorylation phospho.ELM   PhosphoSitePlus 22067460
S30 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
R32 Methylation PhosphoSitePlus
K41 Ubiquitination PhosphoSitePlus
T49 Phosphorylation P24941 (CDK2) phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18847512, 16565220, ...22067460, 18669648, 20068231
K62 Ubiquitination PhosphoSitePlus
S70 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S78 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231, ...16565220
T79 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S81 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 16964243, 16565220, ...18669648, 19690332, 20068231
S87 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 22067460, 18669648, 23186163, ...20068231
S89 Phosphorylation PhosphoSitePlus   UniProt 23186163
S90 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S92 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231, ...16565220
S96 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 20068231, 16565220
T98 Phosphorylation PhosphoSitePlus
Y111 Phosphorylation PhosphoSitePlus
C114 Methylation IEDB 31844290
K122 Ubiquitination PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
K142 Ubiquitination PhosphoSitePlus
K144 Ubiquitination PhosphoSitePlus
T146 Phosphorylation PhosphoSitePlus
K152 Methylation PhosphoSitePlus
K152 Ubiquitination PhosphoSitePlus
T157 Phosphorylation PhosphoSitePlus
K163 Ubiquitination PhosphoSitePlus
Y165 Phosphorylation PhosphoSitePlus
Y177 Phosphorylation PhosphoSitePlus
K185 Acetylation PhosphoSitePlus
K185 Ubiquitination PhosphoSitePlus
S189 Phosphorylation PhosphoSitePlus
S201 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 16565220, 22067460, ...18669648, 20068231
T203 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T207 Phosphorylation PhosphoSitePlus
S233 Phosphorylation PhosphoSitePlus   UniProt 23186163
K238 Ubiquitination PhosphoSitePlus
C316 Methylation IEDB 31844290
S335 Phosphorylation phospho.ELM   PhosphoSitePlus 16565220
K394 Ubiquitination PhosphoSitePlus
C397 Methylation IEDB 31844290
S401 Phosphorylation PhosphoSitePlus
S408 Phosphorylation PhosphoSitePlus
K424 Ubiquitination PhosphoSitePlus
Y428 Phosphorylation PhosphoSitePlus
S429 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Y430 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S432 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 22067460, 18669648, 20068231
K488 Ubiquitination PhosphoSitePlus
K495 Ubiquitination PhosphoSitePlus
S496 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y514 Phosphorylation PhosphoSitePlus
K532 Ubiquitination PhosphoSitePlus
S570 Phosphorylation P68400 (CSNK2A1) PRO   PhosphoSitePlus 17066080
S589 Phosphorylation PhosphoSitePlus
T598 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 22067460, 18669648, 20068231
T605 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 22067460, 18669648, 23186163, ...16565220
T614 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Y616 Phosphorylation PhosphoSitePlus
K630 Ubiquitination PhosphoSitePlus
Y635 Phosphorylation PhosphoSitePlus
K637 Acetylation PhosphoSitePlus   UniProt 19608861
K637 Ubiquitination PhosphoSitePlus
S653 Phosphorylation PhosphoSitePlus
K661 Ubiquitination PhosphoSitePlus
K674 Acetylation PhosphoSitePlus
K674 Ubiquitination PhosphoSitePlus
K685 Ubiquitination PhosphoSitePlus
K692 Acetylation PhosphoSitePlus
K692 Ubiquitination PhosphoSitePlus
C714 Methylation IEDB 31844290
K725 Sumoylation PhosphoSitePlus
K725 Ubiquitination PhosphoSitePlus
S733 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S15 Phosphorylation HPRD 18669648, 19691289, 20068231
S16 Phosphorylation HPRD 18669648, 19691289
S17 Phosphorylation HPRD 18669648, 20068231
S25 Phosphorylation HPRD 17081983, 20068231
S27 Phosphorylation HPRD 17081983
S28 Phosphorylation HPRD 19651622, 20068231
S30 Phosphorylation HPRD 17081983, 20068231, 18212344
T49 Phosphorylation HPRD 18669648, 16565220, 20068231, ...17924679
S70 Phosphorylation HPRD 18669648, 20068231
S78 Phosphorylation HPRD 18669648, 20068231, 16565220
T79 Phosphorylation HPRD 18669648, 20068231
S81 Phosphorylation HPRD 19664995, 16964243, 19691289, ...16565220, 18669648, 20068231
S87 Phosphorylation HPRD 19691289, 19007248, 19664995, ...18669648, 20068231, 20068230
S90 Phosphorylation HPRD 18669648, 19691289
S92 Phosphorylation HPRD 18669648, 20068231, 16565220
S96 Phosphorylation HPRD 20068231, 16565220
S201 Phosphorylation HPRD 18691976, 19007248, 16565220, ...18669648, 18452278, 20068231
T203 Phosphorylation HPRD 18669648
S233 Phosphorylation HPRD 19691289
S329 Phosphorylation HPRD 20068231
S335 Phosphorylation HPRD 16565220
S408 Phosphorylation HPRD 19007248, 20068231
S422 Phosphorylation HPRD 20068231
S429 Phosphorylation HPRD 18669648
Y430 Phosphorylation HPRD 18669648
S432 Phosphorylation HPRD 18669648, 19664994, 19691289, ...20068231
S459 Phosphorylation HPRD 20068231
T598 Phosphorylation HPRD 18669648, 20068231
T605 Phosphorylation HPRD 19413330, 18669648, 16565220
T614 Phosphorylation HPRD 18669648
S653 Phosphorylation HPRD 20068231


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000048525 (hNCAPH/Phos:1) pS570 PRO
PR:000048526 (hNCAPH/PhosThr+) p PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R20 Q20 Biomuta DOID:1324 / lung cancer [ cosmic ]
R32 C32 Biomuta DOID:363 / uterine cancer [ icgc ]
K41 Q41 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T79 N79 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S87 Y87 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S87 P87 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S89 F89 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S92 I92 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S96 L96 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
K152 R152 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S329 N329 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S401 N401 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S408 F408 Biomuta DOID:4159 / skin cancer [ cosmic ]
K495 E495 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S733 Y733 Biomuta DOID:363 / uterine cancer [ icgc ]