iPTMnet Report for Q14CW9 (ATXN7L3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14CW9 / AT7L3_HUMAN
Protein Name Ataxin-7-like protein 3
Gene Name Name: ATXN7L3
Organism Homo sapiens (Human)

PRO ID PR:Q14CW9
DAG View
PRO Name ataxin-7-like protein 3 (human)
Definition An ataxin-7-like protein 3 that is encoded in the genome of human.
Short Label hATXN7L3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14CW9 (ATXN7L3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S129 Phosphorylation PhosphoSitePlus   UniProt 21406692
S131 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163
S157 Phosphorylation HPRD   PhosphoSitePlus 20068231
S163 Phosphorylation PhosphoSitePlus
S180 Phosphorylation PhosphoSitePlus
K184 Acetylation PhosphoSitePlus
S278 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18691976, 19690332
S281 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 21406692, 23186163, ...19664995, 18452278, 18669648, 24275569, 19690332, 20068231
S285 Phosphorylation HPRD 18691976
S288 Phosphorylation HPRD 18691976, 18669648, 19664995, ...20068231, 18452278
T290 Phosphorylation PhosphoSitePlus
K312 Acetylation PhosphoSitePlus
S313 Phosphorylation PhosphoSitePlus
S316 Phosphorylation PhosphoSitePlus
T320 Phosphorylation PhosphoSitePlus
S326 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 20068231
K328 Acetylation PhosphoSitePlus
T339 Phosphorylation PhosphoSitePlus
S341 Phosphorylation PhosphoSitePlus
Y343 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y162 Phosphorylation PhosphoSitePlus
S170 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y162 C162 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S163 F163 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
S170 F170 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
K184 N184 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S288 C288 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
T290 K290 Biomuta [ cosmic ]
T290 M290 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S316 N316 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
S326 F326 Biomuta DOID:4159 / skin cancer [ cosmic ]
K328 N328 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]