iPTMnet Report for Q14CN4 (KRT72)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14CN4 / K2C72_HUMAN
Protein Name Keratin, type II cytoskeletal 72
Gene Name Name: KRT72
Synonyms:K6IRS2,KB35,KRT6,KRT6IRS2;
Organism Homo sapiens (Human)

PRO ID PR:Q14CN4
DAG View
PRO Name keratin, type II cytoskeletal 72 (human)
Definition A keratin, type II cytoskeletal 72 that is encoded in the genome of human.
Short Label hKRT72
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14CN4 (KRT72) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus
K47 Acetylation PhosphoSitePlus
K135 Ubiquitination PhosphoSitePlus
S138 Phosphorylation PhosphoSitePlus
K142 Acetylation PhosphoSitePlus
K142 Ubiquitination PhosphoSitePlus
Y211 Phosphorylation PhosphoSitePlus
K233 Ubiquitination PhosphoSitePlus
K234 Ubiquitination PhosphoSitePlus
Y240 Phosphorylation PhosphoSitePlus
S294 Phosphorylation PhosphoSitePlus
T499 Phosphorylation PhosphoSitePlus
S500 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K362 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K321 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K47 E47 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K135 * Biomuta DOID:4159 / skin cancer [ cosmic ]
K135 M135 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S500 L500 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]