iPTMnet Report for Q14CM0 (FRMPD4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14CM0 / FRPD4_HUMAN
Protein Name FERM and PDZ domain-containing protein 4
Gene Name Name: FRMPD4
Synonyms:KIAA0316,PDZD10,PDZK10;
Organism Homo sapiens (Human)

PRO ID PR:Q14CM0
DAG View
PRO Name FERM and PDZ domain-containing protein 4 (human)
Definition A FERM and PDZ domain-containing protein 4 that is encoded in the genome of human.
Short Label hFRMPD4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14CM0 (FRMPD4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K8 Methylation PhosphoSitePlus
S14 Phosphorylation PhosphoSitePlus
T17 Phosphorylation PhosphoSitePlus
S160 O-Glycosylation GlyGen 30379171, 28411811
Y327 Phosphorylation PhosphoSitePlus
T344 Phosphorylation PhosphoSitePlus
T345 Phosphorylation PhosphoSitePlus
S352 Phosphorylation PhosphoSitePlus
K399 Acetylation PhosphoSitePlus
Y445 Phosphorylation PhosphoSitePlus
S448 Phosphorylation PhosphoSitePlus
T453 Phosphorylation PhosphoSitePlus
S521 O-Glycosylation GlyGen 30379171, 28411811
T571 Phosphorylation PhosphoSitePlus
S585 Phosphorylation PhosphoSitePlus
Y596 Phosphorylation PhosphoSitePlus
Y601 Phosphorylation PhosphoSitePlus
S629 Phosphorylation PhosphoSitePlus
T632 Phosphorylation PhosphoSitePlus
T638 Phosphorylation PhosphoSitePlus
K641 Acetylation PhosphoSitePlus
K650 Acetylation PhosphoSitePlus
Y716 Phosphorylation PhosphoSitePlus
S900 Phosphorylation PhosphoSitePlus
S904 Phosphorylation PhosphoSitePlus
K1028 Ubiquitination PhosphoSitePlus
K1037 Ubiquitination PhosphoSitePlus
K1047 Ubiquitination PhosphoSitePlus
Y1094 Phosphorylation PhosphoSitePlus
S1105 Phosphorylation PhosphoSitePlus
T1114 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T17 S17 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
T345 I345 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K399 M399 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S521 L521 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ]
T571 S571 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S585 R585 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S629 F629 Biomuta DOID:4159 / skin cancer [ cosmic, icgc, tcga ]
T638 A638 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
Y716 * Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S900 T900 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S904 L904 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]