iPTMnet Report for Q14CB8 (ARHGAP19)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14CB8 / RHG19_HUMAN
Protein Name Rho GTPase-activating protein 19
Gene Name Name: ARHGAP19
Organism Homo sapiens (Human)

PRO ID PR:Q14CB8
DAG View
PRO Name Rho GTPase-activating protein 19 (human)
Definition A Rho GTPase-activating protein 19 that is encoded in the genome of human.
Short Label hARHGAP19
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14CB8 (ARHGAP19) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330
S7 Phosphorylation PhosphoSitePlus   UniProt 23186163
K48 Ubiquitination PhosphoSitePlus
S103 Phosphorylation PhosphoSitePlus
K105 Ubiquitination PhosphoSitePlus
K195 Ubiquitination PhosphoSitePlus
K202 Ubiquitination PhosphoSitePlus
K212 Ubiquitination PhosphoSitePlus
K302 Acetylation PhosphoSitePlus
K309 Ubiquitination PhosphoSitePlus
Y322 Phosphorylation PhosphoSitePlus
S325 Phosphorylation PhosphoSitePlus
K331 Ubiquitination PhosphoSitePlus
K343 Ubiquitination PhosphoSitePlus
S344 Phosphorylation PhosphoSitePlus
K349 Ubiquitination PhosphoSitePlus
S350 Phosphorylation PhosphoSitePlus
S358 Phosphorylation PhosphoSitePlus
S386 Phosphorylation PhosphoSitePlus
K388 Ubiquitination PhosphoSitePlus
K398 Ubiquitination PhosphoSitePlus
T404 Phosphorylation PhosphoSitePlus
K416 Ubiquitination PhosphoSitePlus
S420 Phosphorylation PhosphoSitePlus
S422 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 29420299, 18669648, 23186163
S424 Phosphorylation PhosphoSitePlus
K428 Ubiquitination PhosphoSitePlus
K430 Ubiquitination PhosphoSitePlus
S438 Phosphorylation PhosphoSitePlus   UniProt 23186163
K440 Ubiquitination PhosphoSitePlus
T446 Phosphorylation PhosphoSitePlus
K456 Ubiquitination PhosphoSitePlus
S470 Phosphorylation PhosphoSitePlus   UniProt 19690332
T474 Phosphorylation PhosphoSitePlus
T476 Phosphorylation PhosphoSitePlus 18847512
T476 Phosphorylation P24941 (CDK2) PhosphoSitePlus 18847512
T478 Phosphorylation PhosphoSitePlus   UniProt 18847512, 19690332
T478 Phosphorylation P24941 (CDK2) PhosphoSitePlus 18847512
Site PTM Type PTM Enzyme Score Source PMID
S422 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y322 C322 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K331 Q331 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K331 T331 Biomuta DOID:4159 / skin cancer [ cosmic ]
K343 T343 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K416 M416 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S420 L420 Biomuta [ cosmic ] DOID:5041 / esophageal cancer [ cosmic, icgc ]
K440 N440 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]