iPTMnet Report for Q14999 (CUL7)
Protein Information
| UniProt AC / UniProt ID | Q14999 / CUL7_HUMAN |
| Protein Name | Cullin-7 |
| Gene Name | Name: CUL7 Synonyms:KIAA0076; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q14999 |
| PRO Name | cullin-7 (human) |
| Definition | A cullin-7 that is encoded in the genome of human. |
| Short Label | hCUL7 |
| Category | organism-gene |
DAG ViewQ14999 (CUL7) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S105 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K255 | Ubiquitination | score1 | PhosphoSitePlus | |||
| R319 | Methylation | score1 | PhosphoSitePlus | |||
| S326 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S329 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| S339 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648 | ||
| Y369 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y372 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y446 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K567 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S581 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K610 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S616 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K633 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K653 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K765 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K843 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K855 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K970 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S1124 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1129 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1137 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1144 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K1153 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S1183 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K1312 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K1339 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K1431 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S1531 | Phosphorylation | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S326 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S329 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
| S339 | Phosphorylation | score0 | HPRD | 18669648 |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T44 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T281 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S286 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S288 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S329 | C329 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
| S339 | R339 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| Y446 | F446 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| K653 | * | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| S1129 | F1129 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| T1144 | A1144 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| T1144 | M1144 | Biomuta | DOID:4362 / cervical cancer [ cosmic, icgc ] DOID:4606 / bile duct cancer [ cosmic ] | |
| K1431 | N1431 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
| S1531 | N1531 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] |
