iPTMnet Report for Q14980 (NUMA1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14980 / NUMA1_HUMAN
Protein Name Nuclear mitotic apparatus protein 1
Gene Name Name: NUMA1
Synonyms:NMP22;
Organism Homo sapiens (Human)

PRO ID PR:Q14980
DAG View
PRO Name nuclear mitotic apparatus protein 1 (human)
Definition A nuclear mitotic apparatus protein 1 that is encoded in the genome of human.
Short Label hNUMA1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14980 (NUMA1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T2 Phosphorylation PhosphoSitePlus
T6 Phosphorylation PhosphoSitePlus   RLIMS-P 20109190
R42 Methylation PhosphoSitePlus
T46 Phosphorylation PhosphoSitePlus
K54 Ubiquitination PhosphoSitePlus
K73 Ubiquitination PhosphoSitePlus
S76 Phosphorylation PhosphoSitePlus
S77 Phosphorylation PhosphoSitePlus
C80 S-Nitrosylation dbSNO 26338901, 22178444
S91 Phosphorylation PhosphoSitePlus
T107 Phosphorylation PhosphoSitePlus
S112 Phosphorylation PhosphoSitePlus
K153 Ubiquitination PhosphoSitePlus
S158 O-Glycosylation GlyGen 23301498, 35138101, 31492838, ...35289036, 29351928, 33465208, 16408927, 34725712, 32119511, 32574038, 35132862, 28657654, 27655845, 34846842, 33214551, 26853435, 30059200, 35254053, 34019948, 35083852, 28510447, 34229054, 20068230
T159 O-Glycosylation GlyGen 23301498, 35138101, 31492838, ...35289036, 29351928, 33465208, 16408927, 34725712, 32119511, 32574038, 35132862, 28657654, 27655845, 34846842, 33214551, 26853435, 30059200, 35254053, 34019948, 35083852, 28510447, 34229054, 20068230
S161 Phosphorylation PhosphoSitePlus
S162 Phosphorylation PhosphoSitePlus   UniProt 24275569
T163 Phosphorylation PhosphoSitePlus   UniProt 24275569
S169 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 16565220, 18669648, ...24275569, 20068231
S172 Phosphorylation phospho.ELM   PhosphoSitePlus 16565220
K176 Ubiquitination PhosphoSitePlus
S198 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S200 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 16565220
S203 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332, 20068231, ...16565220
T211 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231, 16565220
K247 Ubiquitination PhosphoSitePlus
K267 Ubiquitination PhosphoSitePlus
S271 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231, 24275569
K284 Ubiquitination PhosphoSitePlus
K297 Ubiquitination PhosphoSitePlus
K303 Acetylation PhosphoSitePlus
R311 Methylation PhosphoSitePlus
K312 Ubiquitination PhosphoSitePlus
K326 Ubiquitination PhosphoSitePlus
K358 Ubiquitination PhosphoSitePlus
K364 Ubiquitination PhosphoSitePlus
K379 Acetylation PhosphoSitePlus   UniProt 19608861
K379 Ubiquitination PhosphoSitePlus
K386 Ubiquitination PhosphoSitePlus
S388 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17525332
S395 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 17525332, 30812030
K405 Ubiquitination PhosphoSitePlus
K419 Ubiquitination PhosphoSitePlus
T441 Phosphorylation PhosphoSitePlus
K449 Ubiquitination PhosphoSitePlus
K531 Ubiquitination PhosphoSitePlus
K561 Ubiquitination PhosphoSitePlus
T587 Phosphorylation PhosphoSitePlus
S595 Phosphorylation PhosphoSitePlus
K604 Ubiquitination PhosphoSitePlus
K616 Ubiquitination PhosphoSitePlus
S633 Phosphorylation PhosphoSitePlus
T636 Phosphorylation PhosphoSitePlus
S637 Phosphorylation PhosphoSitePlus
K697 Ubiquitination PhosphoSitePlus
K708 Ubiquitination PhosphoSitePlus
K740 Ubiquitination PhosphoSitePlus
S745 O-Glycosylation GlyGen 23301498, 35138101, 31492838, ...35289036, 29351928, 33465208, 16408927, 34725712, 32119511, 32574038, 35132862, 28657654, 27655845, 34846842, 33214551, 26853435, 30059200, 35254053, 34019948, 35083852, 28510447, 34229054, 20068230
K751 Acetylation PhosphoSitePlus
K755 Ubiquitination PhosphoSitePlus
S801 Phosphorylation PhosphoSitePlus
C803 Methylation IEDB 31844290
S820 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17525332
K855 Ubiquitination PhosphoSitePlus
K891 Acetylation PhosphoSitePlus   UniProt 19608861
K891 Ubiquitination PhosphoSitePlus
K897 Ubiquitination PhosphoSitePlus
K908 Ubiquitination PhosphoSitePlus
K914 Ubiquitination PhosphoSitePlus
S934 Phosphorylation PhosphoSitePlus
K939 Ubiquitination PhosphoSitePlus
S962 O-Glycosylation GlyGen 23301498, 35138101, 31492838, ...35289036, 29351928, 33465208, 16408927, 34725712, 32119511, 32574038, 35132862, 28657654, 27655845, 34846842, 33214551, 26853435, 30059200, 35254053, 34019948, 35083852, 28510447, 34229054, 20068230
T963 O-Glycosylation GlyGen 23301498, 35138101, 31492838, ...35289036, 29351928, 33465208, 16408927, 34725712, 32119511, 32574038, 35132862, 28657654, 27655845, 34846842, 33214551, 26853435, 30059200, 35254053, 34019948, 35083852, 28510447, 34229054, 20068230
T963 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
S991 Phosphorylation PhosphoSitePlus
K1024 Ubiquitination PhosphoSitePlus
T1047 Phosphorylation UniProt 22327364
K1059 Ubiquitination PhosphoSitePlus
K1068 Ubiquitination PhosphoSitePlus
K1078 Ubiquitination PhosphoSitePlus
S1103 Phosphorylation PhosphoSitePlus
S1105 Phosphorylation PhosphoSitePlus
S1109 Phosphorylation PhosphoSitePlus
K1121 Acetylation PhosphoSitePlus
K1121 Ubiquitination PhosphoSitePlus
K1131 Ubiquitination PhosphoSitePlus
K1138 Ubiquitination PhosphoSitePlus
S1145 Phosphorylation PhosphoSitePlus
S1149 Phosphorylation PhosphoSitePlus
K1174 Ubiquitination PhosphoSitePlus
S1187 Phosphorylation PhosphoSitePlus   UniProt 20068231
S1203 Phosphorylation PhosphoSitePlus
K1210 Ubiquitination PhosphoSitePlus
K1223 Ubiquitination PhosphoSitePlus
S1225 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 20068231, 18669648, 19690332, ...24275569
S1228 Phosphorylation PhosphoSitePlus
S1229 Phosphorylation PhosphoSitePlus
S1262 Phosphorylation phospho.ELM   PhosphoSitePlus 16565220
S1278 Phosphorylation PhosphoSitePlus
S1280 Phosphorylation PhosphoSitePlus
T1316 O-Glycosylation GlyGen 33465208
S1317 O-Glycosylation GlyGen 23301498, 35138101, 31492838, ...35289036, 29351928, 33465208, 16408927, 34725712, 32119511, 32574038, 35132862, 28657654, 27655845, 34846842, 33214551, 26853435, 30059200, 35254053, 34019948, 35083852, 28510447, 34229054, 20068230
K1330 Ubiquitination PhosphoSitePlus
K1335 Ubiquitination PhosphoSitePlus
K1339 Ubiquitination PhosphoSitePlus
K1364 Ubiquitination PhosphoSitePlus
C1367 S-Nitrosylation dbSNO 26338901
K1379 Ubiquitination PhosphoSitePlus
K1389 Ubiquitination PhosphoSitePlus
K1430 Ubiquitination PhosphoSitePlus
S1438 Phosphorylation PhosphoSitePlus
K1441 Ubiquitination PhosphoSitePlus
K1442 Ubiquitination PhosphoSitePlus
R1452 Methylation PhosphoSitePlus
K1475 Ubiquitination PhosphoSitePlus
T1489 O-Glycosylation GlyGen 23301498, 35138101, 31492838, ...35289036, 29351928, 33465208, 16408927, 34725712, 32119511, 32574038, 35132862, 28657654, 27655845, 34846842, 33214551, 26853435, 30059200, 35254053, 34019948, 35083852, 28510447, 34229054, 20068230
T1489 Phosphorylation PhosphoSitePlus
T1509 Phosphorylation PhosphoSitePlus
K1511 Acetylation PhosphoSitePlus   UniProt 19608861
K1511 Ubiquitination PhosphoSitePlus
K1518 Ubiquitination PhosphoSitePlus
K1573 Ubiquitination PhosphoSitePlus
S1582 Phosphorylation PhosphoSitePlus
S1601 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17525332
K1603 Ubiquitination PhosphoSitePlus
K1624 Acetylation PhosphoSitePlus
K1625 Ubiquitination PhosphoSitePlus
K1643 Ubiquitination PhosphoSitePlus
K1665 Ubiquitination PhosphoSitePlus
K1699 Ubiquitination PhosphoSitePlus
T1704 Phosphorylation PhosphoSitePlus
K1708 Ubiquitination PhosphoSitePlus
K1715 Ubiquitination PhosphoSitePlus
S1721 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 16565220
S1724 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 16565220
S1728 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
T1733 Phosphorylation phospho.ELM   PhosphoSitePlus 16565220
S1739 Phosphorylation phospho.ELM 15302935
K1740 Ubiquitination PhosphoSitePlus
T1744 Phosphorylation PhosphoSitePlus
T1749 Phosphorylation PhosphoSitePlus
S1750 Phosphorylation PhosphoSitePlus
S1757 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17525332, 23186163, 17081983, ...18220336, 15302935, 21406692, 19367720, 18669648, 24275569, 19690332, 20068231, 16964243
S1760 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17525332
K1766 Acetylation PhosphoSitePlus
K1766 Sumoylation PhosphoSitePlus
K1766 Ubiquitination PhosphoSitePlus
S1769 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 16964243, 16565220, ...18669648, 19690332, 20068231, 22327364
S1772 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 22327364, 16565220
Y1774 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 15592455, 18669648, 22252550
Y1774 Phosphorylation P00519 (ABL1) PhosphoSitePlus 22252550
T1776 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 16964243, 18847512, 16565220, ...18669648, 19690332
T1776 Phosphorylation P24941 (CDK2) PhosphoSitePlus 18847512
S1782 O-Glycosylation GlyGen 34846842
S1782 Phosphorylation PhosphoSitePlus
S1788 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332, 24275569
S1789 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 22327364
S1792 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S1800 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
R1802 Methylation PhosphoSitePlus
T1804 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23097092
T1804 Phosphorylation O14965 (AURKA) PhosphoSitePlus 23097092
S1806 Phosphorylation PhosphoSitePlus
T1811 Phosphorylation PhosphoSitePlus 22267324, 23097092
T1811 Phosphorylation O14965 (AURKA) PhosphoSitePlus 23097092
T1811 Phosphorylation Q96GD4 (AURKB) PhosphoSitePlus 22267324
T1812 Phosphorylation PhosphoSitePlus 23097092
T1812 Phosphorylation O14965 (AURKA) PhosphoSitePlus 23097092
T1818 Phosphorylation PhosphoSitePlus
T1820 Phosphorylation PhosphoSitePlus
K1822 Acetylation PhosphoSitePlus
K1822 Ubiquitination PhosphoSitePlus
S1830 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231, ...16565220
S1833 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 16565220
S1834 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15302935, 18669648, 23186163, ...22327364
Y1836 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S1837 O-Glycosylation GlyGen 23301498, 35138101, 31492838, ...35289036, 29351928, 33465208, 16408927, 34725712, 32119511, 32574038, 35132862, 28657654, 27655845, 34846842, 33214551, 26853435, 30059200, 35254053, 34019948, 35083852, 28510447, 34229054, 20068230
S1837 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 16565220
T1838 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1840 O-Glycosylation GlyGen 23301498, 35138101, 31492838, ...35289036, 29351928, 33465208, 16408927, 34725712, 32119511, 32574038, 35132862, 28657654, 27655845, 34846842, 33214551, 26853435, 30059200, 35254053, 34019948, 35083852, 28510447, 34229054, 20068230
S1840 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 16964243
S1844 O-Glycosylation GlyGen   PhosphoSitePlus   UniProt 23301498, 35138101, 30620550, ...31492838, 35289036, 35254053, 33465208, 16408927, 34725712, 32119511, 32574038, 35132862, 28657654, 27655845, 34846842, 33214551, 26853435, 30059200, 29351928, 34019948, 35083852, 28510447, 34229054, 20068230
S1844 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1847 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29351928, 33465208, 16408927, 34725712, 32119511, 32574038, 35132862, 28657654, 27655845, 34846842, 33214551, 26853435, 30059200, 35254053, 34019948, 35083852, 28510447, 34229054, 20068230
S1847 Phosphorylation phospho.ELM   PhosphoSitePlus 16964243
R1849 Methylation PhosphoSitePlus
T1851 O-Glycosylation GlyGen 32574038
S1852 Phosphorylation PhosphoSitePlus
S1853 Phosphorylation phospho.ELM   PhosphoSitePlus 15302935
T1854 O-Glycosylation GlyGen 32574038
T1854 Phosphorylation PhosphoSitePlus
R1859 Methylation PhosphoSitePlus
S1862 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 16565220, ...18669648, 20068231
Y1865 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1868 Phosphorylation PhosphoSitePlus
S1872 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 16565220
Y1876 Phosphorylation phospho.ELM 18669648
R1877 Methylation PhosphoSitePlus
T1879 Phosphorylation PhosphoSitePlus
T1880 Phosphorylation PhosphoSitePlus
S1882 Phosphorylation PhosphoSitePlus
S1883 Phosphorylation PhosphoSitePlus
S1887 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23097092, 18669648, 23186163
S1887 Phosphorylation O14965 (AURKA) PhosphoSitePlus 23097092
S1892 Phosphorylation PhosphoSitePlus
S1901 Phosphorylation PhosphoSitePlus
Y1903 Phosphorylation PhosphoSitePlus
C1930 Methylation IEDB 31844290
K1935 Ubiquitination PhosphoSitePlus
T1936 Phosphorylation PhosphoSitePlus
S1942 Phosphorylation PhosphoSitePlus
S1945 Phosphorylation phospho.ELM   PhosphoSitePlus 16565220
S1947 Phosphorylation PhosphoSitePlus
T1950 Phosphorylation PhosphoSitePlus
T1952 Phosphorylation PhosphoSitePlus
K1957 Ubiquitination PhosphoSitePlus
T1964 Phosphorylation PhosphoSitePlus
S1969 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P+   UniProt 23186163, 18220336, 26832443, ...18669648, 22267324, 20068231
S1969 Phosphorylation O14965 (AURKA) RLIMS-P+ 26832443
S1969 Phosphorylation Q96GD4 (AURKB) PhosphoSitePlus 22267324
K1988 Acetylation PhosphoSitePlus
S1991 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P+   UniProt 23186163, 26832443, 18669648, ...23097092, 20068231
S1991 Phosphorylation O14965 (AURKA) PhosphoSitePlus   RLIMS-P+ 26832443, 23097092
T2000 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 16565220, ...18669648, 20068231
S2003 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17081983, 20068231
K2004 Acetylation PhosphoSitePlus
K2004 Ubiquitination PhosphoSitePlus
T2015 Phosphorylation PhosphoSitePlus   UniProt 7769006, 23921553
T2015 Phosphorylation P06493 (CDK1) PhosphoSitePlus 23921553
S2026 Phosphorylation PhosphoSitePlus
T2027 Phosphorylation PhosphoSitePlus
T2028 Phosphorylation PhosphoSitePlus
K2032 Acetylation PhosphoSitePlus
K2040 Acetylation PhosphoSitePlus
S2047 Phosphorylation PhosphoSitePlus   RLIMS-P+   UniProt 22267324, 26832443, 23097092, ...23186163
S2047 Phosphorylation O14965 (AURKA) PhosphoSitePlus   RLIMS-P+ 26832443, 23097092
S2047 Phosphorylation Q96GD4 (AURKB) PhosphoSitePlus 22267324
S2051 Phosphorylation PhosphoSitePlus
T2055 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 23186163, 16964243, 18234856, ...7769006, 24109598, 22267324, 23921553
T2055 Phosphorylation P06493 (CDK1) PhosphoSitePlus   Signor 18234856, 23921553
T2055 Phosphorylation Q96GD4 (AURKB) PhosphoSitePlus 22267324
K2057 Acetylation PhosphoSitePlus
K2058 Acetylation PhosphoSitePlus
S2062 Phosphorylation PhosphoSitePlus   UniProt 23186163
S2069 Phosphorylation IEDB 31848261
K2070 Acetylation PhosphoSitePlus
K2071 Acetylation PhosphoSitePlus
S2074 Phosphorylation PhosphoSitePlus
S2077 Phosphorylation PhosphoSitePlus   UniProt 17924679
T2080 Phosphorylation PhosphoSitePlus
T2084 Phosphorylation PhosphoSitePlus 23097092
T2084 Phosphorylation O14965 (AURKA) PhosphoSitePlus 23097092
S2087 Phosphorylation PhosphoSitePlus   UniProt 7769006, 23097092, 23921553
S2087 Phosphorylation O14965 (AURKA) PhosphoSitePlus 23097092
S2087 Phosphorylation P06493 (CDK1) PhosphoSitePlus 23921553
T2092 O-Glycosylation GlyGen 23301498, 35138101, 31492838, ...35289036, 29351928, 33465208, 16408927, 34725712, 31373491, 32119511, 32574038, 35132862, 28657654, 27655845, 34846842, 33214551, 26853435, 30059200, 35254053, 34019948, 35083852, 28510447, 34229054, 20068230
T2093 O-Glycosylation GlyGen 23301498, 35138101, 31492838, ...35289036, 29351928, 33465208, 16408927, 34725712, 32119511, 32574038, 32938750, 35132862, 28657654, 27655845, 34846842, 33214551, 26853435, 30059200, 35254053, 34019948, 35083852, 28510447, 34229054, 20068230
T2094 O-Glycosylation GlyGen 34846842
T2099 Phosphorylation PhosphoSitePlus
T2106 O-Glycosylation GlyGen 34846842
T2106 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 7769006, 16964243, 23921553
T2106 Phosphorylation P06493 (CDK1) PhosphoSitePlus 23921553
K2114 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T2 Phosphorylation HPRD 20068231
T6 Phosphorylation HPRD 20068231
T46 Phosphorylation HPRD 20068231
S169 Phosphorylation HPRD 19691289, 16565220, 18669648, ...20166139, 18452278, 19415658, 20068231
S172 Phosphorylation HPRD 20166139, 16565220
S189 Phosphorylation HPRD 20068231
S198 Phosphorylation HPRD 18669648, 20068231
S200 Phosphorylation HPRD 18669648, 19007248, 20068231, ...16565220
S203 Phosphorylation HPRD 18669648, 20068231, 16565220
T211 Phosphorylation HPRD 18669648, 20068231, 16565220
S271 Phosphorylation HPRD 19007248, 20068231, 19691289
T289 Phosphorylation HPRD 17081983
S388 Phosphorylation HPRD 17525332
S395 Phosphorylation HPRD 17525332, 18077418, 20068231
S820 Phosphorylation HPRD 17525332
T963 Phosphorylation HPRD 17525332
S1187 Phosphorylation HPRD 20068231
S1225 Phosphorylation HPRD 18669648, 20068231, 18452278
S1235 Phosphorylation HPRD 20068231
S1262 Phosphorylation HPRD 16565220, 20068231, 20068230
S1280 Phosphorylation HPRD 19007248
S1438 Phosphorylation HPRD 20068231
S1601 Phosphorylation HPRD 17525332
S1721 Phosphorylation HPRD 18669648, 16565220
S1724 Phosphorylation HPRD 18669648, 16565220
S1728 Phosphorylation HPRD 18669648, 17081983
T1733 Phosphorylation HPRD 16565220
T1744 Phosphorylation HPRD 18077418
S1750 Phosphorylation HPRD 19651622
S1757 Phosphorylation HPRD 19413330, 19664995, 18491316, ...20058876, 18212344, 18767875, 18077418, 15302935, 19691289, 18452278, 19007248, 19651622, 19664994, 18669648, 20166139, 16565220, 17924679, 19415658, 20068231, 16964243
S1760 Phosphorylation HPRD 17525332, 18452278
S1769 Phosphorylation HPRD 18669648, 16565220, 16964243, ...20068231, 18452278
S1772 Phosphorylation HPRD 18669648, 16565220
Y1774 Phosphorylation HPRD 15592455, 18669648
T1776 Phosphorylation HPRD 18669648, 16964243, 16565220
S1788 Phosphorylation HPRD 18669648, 20068231, 18452278
S1789 Phosphorylation HPRD 18669648, 20068231
S1792 Phosphorylation HPRD 18669648, 16964243, 20068231
S1800 Phosphorylation HPRD 18669648, 16964243
T1804 Phosphorylation HPRD 18669648
T1811 Phosphorylation HPRD 19691289
S1830 Phosphorylation HPRD 18669648, 16565220, 19691289, ...20068231, 19007248
S1833 Phosphorylation HPRD 18669648, 16565220
S1834 Phosphorylation HPRD 18669648, 16565220
Y1836 Phosphorylation HPRD 18669648
S1837 Phosphorylation HPRD 18669648, 16565220
T1838 Phosphorylation HPRD 18669648
S1840 Phosphorylation HPRD 18669648, 19007248, 19691289, ...20068231, 16964243
S1844 Phosphorylation HPRD 19691289, 20068231
S1847 Phosphorylation HPRD 19007248, 19691289, 16964243
S1853 Phosphorylation HPRD 15302935, 20068231
T1854 Phosphorylation HPRD 20068231
S1862 Phosphorylation HPRD 19651622, 18669648, 19007248, ...20068231, 16565220
Y1865 Phosphorylation HPRD 18669648, 17081983
S1868 Phosphorylation HPRD 17081983
S1872 Phosphorylation HPRD 18669648, 16565220
Y1876 Phosphorylation HPRD 18669648
S1887 Phosphorylation HPRD 18669648, 19007248, 19691289, ...18212344
S1945 Phosphorylation HPRD 20068231, 16565220
S1947 Phosphorylation HPRD 20068231
T1958 Phosphorylation HPRD 20068231
T1964 Phosphorylation HPRD 20068231
S1969 Phosphorylation HPRD 18669648, 18212344, 20068231, ...19691289
S1991 Phosphorylation HPRD 18669648, 19691289, 20068231
T2000 Phosphorylation HPRD 19664995, 19691289, 16565220, ...19651622, 18669648, 20068231
S2003 Phosphorylation HPRD 17081983, 20068231
S2047 Phosphorylation HPRD 18212344
S2051 Phosphorylation HPRD 20068231
T2055 Phosphorylation HPRD 18212344, 19664995, 20068231, ...16964243
S2062 Phosphorylation HPRD 18212344, 19691289
S2074 Phosphorylation HPRD 19007248, 20068231
S2077 Phosphorylation HPRD 19007248, 20068231, 17924679
T2080 Phosphorylation HPRD 20068231
T2106 Phosphorylation HPRD 16964243, 18212344, 19007248, ...19691289
Site PTM Type PTM Enzyme Score Source PMID
K1532 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K1715 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R42 K42 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic, icgc ]
T107 A107 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S189 F189 Biomuta DOID:4159 / skin cancer [ cosmic ]
S198 L198 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
R311 L311 Biomuta DOID:3571 / liver cancer [ cosmic ]
R311 H311 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K312 R312 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S395 P395 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S595 F595 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K1059 N1059 Biomuta DOID:363 / uterine cancer [ icgc ]
K1138 M1138 Biomuta DOID:3571 / liver cancer [ cosmic ]
S1187 L1187 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S1187 W1187 Biomuta DOID:1324 / lung cancer [ cosmic ]
T1316 A1316 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K1339 T1339 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K1430 E1430 Biomuta DOID:1324 / lung cancer [ cosmic ]
K1430 T1430 Biomuta DOID:1324 / lung cancer [ cosmic ]
R1452 W1452 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:4606 / bile duct cancer [ cosmic ]
T1509 P1509 Biomuta DOID:363 / uterine cancer [ icgc ]
K1518 N1518 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
K1573 T1573 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S1582 R1582 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
K1603 N1603 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K1624 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K1708 N1708 Biomuta DOID:1612 / breast cancer [ cosmic ]
S1760 C1760 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K1766 T1766 Biomuta DOID:10283 / prostate cancer [ cosmic ]
T1776 S1776 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S1800 L1800 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1800 W1800 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R1802 H1802 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
R1802 C1802 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:2531 / hematologic cancer [ icgc ]
S1834 L1834 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
Y1836 C1836 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
Y1836 H1836 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T1838 M1838 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1840 F1840 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T1851 A1851 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
S1852 Y1852 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1872 R1872 Biomuta DOID:3953 / adrenal gland cancer [ cosmic ]
R1877 C1877 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S1882 N1882 Biomuta DOID:363 / uterine cancer [ icgc ]
S1945 F1945 Biomuta [ cosmic ]
T1958 S1958 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T2015 I2015 Biomuta [ cosmic ]
T2028 I2028 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic ]
S2047 L2047 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S2051 N2051 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K2057 E2057 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S2062 N2062 Biomuta DOID:263 / kidney cancer [ cosmic ]
T2080 P2080 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T2084 P2084 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ]