iPTMnet Report for Q14966 (ZNF638)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14966 / ZN638_HUMAN
Protein Name Zinc finger protein 638
Gene Name Name: ZNF638
Synonyms:NP220;
Organism Homo sapiens (Human)

PRO ID PR:Q14966
DAG View
PRO Name zinc finger protein 638 (human)
Definition A zinc finger protein 638 that is encoded in the genome of human.
Short Label hZNF638
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14966 (ZNF638) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R33 Methylation PhosphoSitePlus
S36 Phosphorylation PhosphoSitePlus
R41 Methylation PhosphoSitePlus
R47 Methylation PhosphoSitePlus   UniProt 24129315
R49 Methylation PhosphoSitePlus   UniProt 24129315
R54 Methylation PhosphoSitePlus   UniProt 24129315
Y61 Phosphorylation PhosphoSitePlus
R68 Methylation PhosphoSitePlus
R81 Methylation PhosphoSitePlus
K86 Ubiquitination PhosphoSitePlus
T125 Phosphorylation PhosphoSitePlus
S128 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 16964243, ...15302935, 18669648, 19690332, 20068231
K130 Ubiquitination PhosphoSitePlus
S193 Phosphorylation PhosphoSitePlus
K196 Ubiquitination PhosphoSitePlus
K216 Ubiquitination PhosphoSitePlus
S283 Phosphorylation PhosphoSitePlus
S289 Phosphorylation PhosphoSitePlus   UniProt 23186163
S299 Phosphorylation PhosphoSitePlus   UniProt 23186163
S303 Phosphorylation PhosphoSitePlus
S366 Phosphorylation PhosphoSitePlus
R367 Methylation PhosphoSitePlus
S369 Phosphorylation PhosphoSitePlus   UniProt 23186163
K371 Ubiquitination PhosphoSitePlus
S375 Phosphorylation PhosphoSitePlus 21851590
S375 Phosphorylation O14757 (CHEK1) PhosphoSitePlus 21851590
R382 Methylation PhosphoSitePlus
S383 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
T409 Phosphorylation PhosphoSitePlus
S420 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
C454 Methylation IEDB 31844290
T483 Phosphorylation PhosphoSitePlus
S488 Phosphorylation PhosphoSitePlus
S490 Phosphorylation PhosphoSitePlus
S492 Phosphorylation PhosphoSitePlus
S499 Phosphorylation PhosphoSitePlus
S502 Phosphorylation PhosphoSitePlus
S508 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S510 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S520 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S522 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S541 Phosphorylation PhosphoSitePlus
Y543 Phosphorylation PhosphoSitePlus
R544 Methylation PhosphoSitePlus
R546 Methylation PhosphoSitePlus
S552 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 17081983, ...20068231
R557 Methylation PhosphoSitePlus
S558 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 17081983
S560 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 17081983
S568 Phosphorylation PhosphoSitePlus
S571 Phosphorylation PhosphoSitePlus
K576 Ubiquitination PhosphoSitePlus
S585 Phosphorylation PhosphoSitePlus
T589 Phosphorylation PhosphoSitePlus
K593 Ubiquitination PhosphoSitePlus
K602 Ubiquitination PhosphoSitePlus
S605 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 16565220, ...24275569, 17924679
T612 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S614 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
T616 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T623 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S624 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T626 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S628 Phosphorylation PhosphoSitePlus
S630 Phosphorylation PhosphoSitePlus
S636 Phosphorylation PhosphoSitePlus   UniProt 23186163
S641 Phosphorylation PhosphoSitePlus
S650 Phosphorylation PhosphoSitePlus
K653 Ubiquitination PhosphoSitePlus
S656 Phosphorylation PhosphoSitePlus
K658 Ubiquitination PhosphoSitePlus
S671 Phosphorylation PhosphoSitePlus
Y716 Phosphorylation PhosphoSitePlus
Y731 Phosphorylation PhosphoSitePlus
T738 Phosphorylation PhosphoSitePlus
S770 Phosphorylation PhosphoSitePlus
T773 Phosphorylation PhosphoSitePlus
S789 O-Glycosylation GlyGen 23301498, 33214551, 32938750, ...35138101, 30379171, 34725712, 35254053, 34019948, 32119511
S791 Phosphorylation PhosphoSitePlus
T795 Phosphorylation PhosphoSitePlus
S801 Phosphorylation PhosphoSitePlus
S808 Phosphorylation PhosphoSitePlus
T809 Phosphorylation PhosphoSitePlus
S815 Phosphorylation PhosphoSitePlus
S818 Phosphorylation PhosphoSitePlus
K853 Acetylation PhosphoSitePlus
K868 Acetylation PhosphoSitePlus
S885 Phosphorylation PhosphoSitePlus
K927 Ubiquitination PhosphoSitePlus
K943 Ubiquitination PhosphoSitePlus
K951 Acetylation PhosphoSitePlus
K951 Ubiquitination PhosphoSitePlus
Y1060 Phosphorylation PhosphoSitePlus
K1098 Ubiquitination PhosphoSitePlus
S1100 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332, ...16565220
S1106 Phosphorylation PhosphoSitePlus
S1119 Phosphorylation PhosphoSitePlus
S1121 Phosphorylation PhosphoSitePlus
S1158 Phosphorylation PhosphoSitePlus
T1328 Phosphorylation PhosphoSitePlus
K1330 Acetylation PhosphoSitePlus
T1376 Phosphorylation PhosphoSitePlus
S1377 Phosphorylation PhosphoSitePlus
K1391 Acetylation PhosphoSitePlus
K1391 Ubiquitination PhosphoSitePlus
S1400 Phosphorylation PhosphoSitePlus
S1401 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 15302935, 21406692
S1409 Phosphorylation PhosphoSitePlus
K1430 Acetylation PhosphoSitePlus
K1430 Ubiquitination PhosphoSitePlus
K1441 Acetylation PhosphoSitePlus
K1455 Acetylation PhosphoSitePlus
S1462 Phosphorylation PhosphoSitePlus
R1465 Methylation PhosphoSitePlus
S1468 Phosphorylation PhosphoSitePlus
S1472 Phosphorylation PhosphoSitePlus
K1477 Acetylation PhosphoSitePlus
K1477 Ubiquitination PhosphoSitePlus
S1479 Phosphorylation PhosphoSitePlus
K1480 Ubiquitination PhosphoSitePlus
S1575 Phosphorylation PhosphoSitePlus
S1641 Phosphorylation PhosphoSitePlus
S1656 Phosphorylation PhosphoSitePlus
S1667 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
K1676 Ubiquitination PhosphoSitePlus
S1697 Phosphorylation PhosphoSitePlus
S1797 Phosphorylation PhosphoSitePlus
S1825 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
T1851 Phosphorylation PhosphoSitePlus
K1860 Acetylation PhosphoSitePlus
K1866 Acetylation PhosphoSitePlus
S1882 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S1888 Phosphorylation PhosphoSitePlus
K1891 Acetylation PhosphoSitePlus
S1893 Phosphorylation PhosphoSitePlus
S1913 Phosphorylation PhosphoSitePlus
S1938 Phosphorylation PhosphoSitePlus
K1958 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T125 Phosphorylation HPRD 19664995, 19691289, 19007248
S128 Phosphorylation HPRD 19413330, 18691976, 16964243, ...19664994, 19007248, 16565220, 19651622, 18669648, 19664995, 20068231, 19691289
S283 Phosphorylation HPRD 19691289
S383 Phosphorylation HPRD 18669648, 20068231, 17924679
S420 Phosphorylation HPRD 18669648
S508 Phosphorylation HPRD 19651622, 17081983, 20068231
S510 Phosphorylation HPRD 19651622, 17081983, 20068231
Y514 Phosphorylation HPRD 20068231
S520 Phosphorylation HPRD 20068231
S522 Phosphorylation HPRD 20068231
S539 Phosphorylation HPRD 20068231
S541 Phosphorylation HPRD 20068231
S552 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231
S558 Phosphorylation HPRD 19413330, 18669648, 17081983, ...20068231
S560 Phosphorylation HPRD 19413330, 18669648, 17081983, ...20068231
S585 Phosphorylation HPRD 20068231
T589 Phosphorylation HPRD 20068231
S605 Phosphorylation HPRD 16565220, 20068231, 17924679
T612 Phosphorylation HPRD 18669648
S614 Phosphorylation HPRD 18669648
T616 Phosphorylation HPRD 18669648
T623 Phosphorylation HPRD 18669648
S624 Phosphorylation HPRD 18669648
T626 Phosphorylation HPRD 18669648
S770 Phosphorylation HPRD 19007248
S1100 Phosphorylation HPRD 19651622, 18669648, 16565220, ...20068231, 18452278
S1243 Phosphorylation HPRD 20068231
S1389 Phosphorylation HPRD 20068231
S1400 Phosphorylation HPRD 20068231
S1401 Phosphorylation HPRD 16964243, 19664995, 19691289, ...18669648, 20068231, 20068230
S1667 Phosphorylation HPRD 19664994, 20068231
S1825 Phosphorylation HPRD 17525332, 18077418
T1848 Phosphorylation HPRD 20068231
S1882 Phosphorylation HPRD 18669648
S1913 Phosphorylation HPRD 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R41 K41 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K216 N216 Biomuta DOID:1324 / lung cancer [ cosmic ]
S283 T283 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K371 N371 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R382 W382 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S420 F420 Biomuta DOID:4159 / skin cancer [ cosmic ]
C454 F454 Biomuta DOID:1324 / lung cancer [ cosmic ]
S488 C488 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S490 F490 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S502 I502 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S508 T508 Biomuta DOID:363 / uterine cancer [ cosmic ]
S541 * Biomuta DOID:3571 / liver cancer [ cosmic ]
S541 L541 Biomuta DOID:1612 / breast cancer [ icgc ]
R544 Q544 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ cosmic, icgc ]
R557 L557 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
R557 * Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ]
S568 L568 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K593 E593 Biomuta DOID:10283 / prostate cancer [ cosmic ]
K593 R593 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T612 I612 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S614 N614 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T616 P616 Biomuta DOID:1324 / lung cancer [ cosmic ]
S636 C636 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S801 Y801 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S808 F808 Biomuta DOID:1612 / breast cancer [ cosmic ]
S815 A815 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S885 Y885 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1121 Y1121 Biomuta DOID:3571 / liver cancer [ cosmic ]
S1409 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S1575 P1575 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1641 L1641 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S1656 F1656 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1667 P1667 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1825 F1825 Biomuta DOID:1612 / breast cancer [ cosmic ]
S1913 P1913 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S1938 * Biomuta DOID:5041 / esophageal cancer [ cosmic ]