iPTMnet Report for Q14940 (SLC9A5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14940 / SL9A5_HUMAN
Protein Name Sodium/hydrogen exchanger 5
Gene Name Name: SLC9A5
Synonyms:NHE5;
Organism Homo sapiens (Human)

PRO ID PR:Q14940
DAG View
PRO Name sodium/hydrogen exchanger 5 (human)
Definition A sodium/hydrogen exchanger 5 that is encoded in the genome of human.
Short Label hSLC9A5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14940 (SLC9A5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S321 Phosphorylation PhosphoSitePlus
K459 Ubiquitination PhosphoSitePlus
S538 Phosphorylation PhosphoSitePlus
S559 Phosphorylation PhosphoSitePlus
S575 Phosphorylation PhosphoSitePlus
S577 Phosphorylation PhosphoSitePlus
S618 Phosphorylation PhosphoSitePlus
S620 Phosphorylation PhosphoSitePlus
T681 Phosphorylation PhosphoSitePlus
S702 Phosphorylation P25098 (GRK2) , P68400 (CSNK2A1) PhosphoSitePlus 21296876
S709 Phosphorylation P68400 (CSNK2A1) , P25098 (GRK2) PhosphoSitePlus 21296876
S711 Phosphorylation P68400 (CSNK2A1) , P25098 (GRK2) PhosphoSitePlus 21296876
S712 Phosphorylation P25098 (GRK2) , P68400 (CSNK2A1) PhosphoSitePlus 21296876
T714 Phosphorylation P68400 (CSNK2A1) , P25098 (GRK2) PhosphoSitePlus 21296876
T729 Phosphorylation PhosphoSitePlus
S741 Phosphorylation PhosphoSitePlus
S747 Phosphorylation PhosphoSitePlus
S851 Phosphorylation PhosphoSitePlus
S853 Phosphorylation PhosphoSitePlus
S855 Phosphorylation PhosphoSitePlus
S856 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S559 G559 Biomuta DOID:263 / kidney cancer [ cosmic ]
S577 N577 Biomuta [ cosmic ]
S853 G853 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S856 N856 Biomuta DOID:3571 / liver cancer [ cosmic ]