iPTMnet Report for Q14938 (NFIX)
Protein Information
| UniProt AC / UniProt ID | Q14938 / NFIX_HUMAN |
| Protein Name | Nuclear factor 1 X-type |
| Gene Name | Name: NFIX |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q14938 |
| PRO Name | nuclear factor 1 X-type (human) |
| Definition | A nuclear factor 1 X-type that is encoded in the genome of human. |
| Short Label | hNFIX |
| Category | organism-gene |
DAG ViewQ14938 (NFIX) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S3 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K57 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K64 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S106 | O-Glycosylation | score1 | GlyGen | 30379171, 28657654 | ||
| T145 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T233 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S244 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S250 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y253 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S265 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| T267 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S268 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S271 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T272 | O-Glycosylation | score1 | GlyGen | 30379171, 28657654 | ||
| T272 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S273 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T274 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S280 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 19690332, 24275569, 18220336 | ||
| S284 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S288 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S301 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S306 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S307 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S309 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S322 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K324 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S336 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S340 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S341 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R343 | Methylation | score1 | PhosphoSitePlus | |||
| S361 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S381 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y383 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T388 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S399 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T463 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S466 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S106 | F106 | Biomuta | DOID:10283 / prostate cancer [ cosmic ] | |
| T233 | S233 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
| S271 | F271 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S301 | F301 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S306 | N306 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S336 | F336 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S341 | Y341 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| R343 | H343 | Biomuta | DOID:10283 / prostate cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic, icgc ] | |
| R343 | C343 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] | |
| S381 | I381 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| Y383 | N383 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] |
