iPTMnet Report for Q14914 (PTGR1)
Protein Information
UniProt AC / UniProt ID | Q14914 / PTGR1_HUMAN |
Protein Name | Prostaglandin reductase 1 |
Gene Name | Name: PTGR1 Synonyms:LTB4DH; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q14914 |
PRO Name | prostaglandin reductase 1 (human) |
Definition | A prostaglandin reductase 1 that is encoded in the genome of human. |
Short Label | hPTGR1 |
Category | organism-gene |
Q14914 (PTGR1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K11 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y16 | Phosphorylation | score1 | PhosphoSitePlus | |||
T18 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
S20 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
T26 | Phosphorylation | score1 | PhosphoSitePlus | |||
K58 | Ubiquitination | score1 | PhosphoSitePlus | |||
K70 | Ubiquitination | score1 | PhosphoSitePlus | |||
S74 | Phosphorylation | score1 | PhosphoSitePlus | |||
K75 | Ubiquitination | score1 | PhosphoSitePlus | |||
S88 | Phosphorylation | score1 | PhosphoSitePlus | |||
K100 | Acetylation | score1 | PhosphoSitePlus | |||
K100 | Ubiquitination | score1 | PhosphoSitePlus | |||
K168 | Ubiquitination | score1 | PhosphoSitePlus | |||
K178 | Ubiquitination | score1 | PhosphoSitePlus | |||
K204 | Ubiquitination | score1 | PhosphoSitePlus | |||
K231 | Acetylation | score1 | PhosphoSitePlus | |||
K232 | Acetylation | score1 | PhosphoSitePlus | |||
Y262 | Phosphorylation | score1 | PhosphoSitePlus | |||
R280 | Methylation | score1 | PhosphoSitePlus | |||
K289 | Acetylation | score1 | PhosphoSitePlus | |||
K289 | Ubiquitination | score1 | PhosphoSitePlus | |||
K324 | Ubiquitination | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K289 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K11 | Q11 | Biomuta | DOID:263 / kidney cancer [ cosmic, icgc ] | |
K75 | E75 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
S88 | Y88 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
K204 | N204 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
K231 | N231 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
R280 | H280 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
R280 | C280 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] |