iPTMnet Report for Q14914 (PTGR1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14914 / PTGR1_HUMAN
Protein Name Prostaglandin reductase 1
Gene Name Name: PTGR1
Synonyms:LTB4DH;
Organism Homo sapiens (Human)

PRO ID PR:Q14914
DAG View
PRO Name prostaglandin reductase 1 (human)
Definition A prostaglandin reductase 1 that is encoded in the genome of human.
Short Label hPTGR1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14914 (PTGR1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K11 Ubiquitination PhosphoSitePlus
Y16 Phosphorylation PhosphoSitePlus
T18 Phosphorylation PhosphoSitePlus   UniProt 24275569
S20 Phosphorylation PhosphoSitePlus   UniProt 24275569
T26 Phosphorylation PhosphoSitePlus
K58 Ubiquitination PhosphoSitePlus
K70 Ubiquitination PhosphoSitePlus
S74 Phosphorylation PhosphoSitePlus
K75 Ubiquitination PhosphoSitePlus
S88 Phosphorylation PhosphoSitePlus
K100 Acetylation PhosphoSitePlus
K100 Ubiquitination PhosphoSitePlus
K168 Ubiquitination PhosphoSitePlus
K178 Ubiquitination PhosphoSitePlus
K204 Ubiquitination PhosphoSitePlus
K231 Acetylation PhosphoSitePlus
K232 Acetylation PhosphoSitePlus
Y262 Phosphorylation PhosphoSitePlus
R280 Methylation PhosphoSitePlus
K289 Acetylation PhosphoSitePlus
K289 Ubiquitination PhosphoSitePlus
K324 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K289 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K11 Q11 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
K75 E75 Biomuta DOID:3571 / liver cancer [ cosmic ]
S88 Y88 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K204 N204 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K231 N231 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R280 H280 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R280 C280 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]