iPTMnet Report for Q14896 (MYBPC3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14896 / MYPC3_HUMAN
Protein Name Myosin-binding protein C, cardiac-type
Gene Name Name: MYBPC3
Organism Homo sapiens (Human)

PRO ID PR:Q14896
DAG View
PRO Name myosin-binding protein C, cardiac-type (human)
Definition A myosin-binding protein C, cardiac-type that is encoded in the genome of human.
Short Label hMYBPC3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14896 (MYBPC3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S18 Phosphorylation PhosphoSitePlus
T59 Phosphorylation PhosphoSitePlus
S78 Phosphorylation PhosphoSitePlus
Y79 Phosphorylation PhosphoSitePlus
S86 Phosphorylation PhosphoSitePlus
S133 Phosphorylation P49841 (GSK3B) PhosphoSitePlus 23277198
S212 Phosphorylation PhosphoSitePlus
Y213 Phosphorylation PhosphoSitePlus
T274 Phosphorylation PhosphoSitePlus
S275 Phosphorylation P22612 (PRKACG) , Q05655 (PRKCD) , P22694 (PRKACB) , P17612 (PRKACA) phospho.ELM   PhosphoSitePlus   Signor 17075052, 20151718, 18802026, ...20018870
S284 Phosphorylation P17612 (PRKACA) , P22694 (PRKACB) , Q05655 (PRKCD) , P22612 (PRKACG) phospho.ELM   PhosphoSitePlus   Signor 17075052, 18802026, 20018870, ...17560599, 20151718
S286 Phosphorylation PhosphoSitePlus
T290 Phosphorylation PhosphoSitePlus
S304 Phosphorylation P17612 (PRKACA) , P22694 (PRKACB) , Q05655 (PRKCD) , P22612 (PRKACG) , Q15139 (PRKD1) neXtProt   phospho.ELM   PhosphoSitePlus   Signor 17075052, 20151718, 18802026, ...20018870
T307 Phosphorylation PhosphoSitePlus
S311 Phosphorylation P22694 (PRKACB) , P17612 (PRKACA) , P22612 (PRKACG) phospho.ELM   PhosphoSitePlus   Signor 20151718
Y340 Phosphorylation PhosphoSitePlus
Y373 Phosphorylation PhosphoSitePlus
T384 O-Glycosylation GlyGen 30379171, 35254053, 26960196, ...23271734
K418 Acetylation PhosphoSitePlus
S424 Phosphorylation PhosphoSitePlus
S427 Phosphorylation PhosphoSitePlus
Y548 Phosphorylation PhosphoSitePlus
S550 Phosphorylation PhosphoSitePlus
S588 Phosphorylation PhosphoSitePlus
T602 Phosphorylation PhosphoSitePlus
T607 Phosphorylation PhosphoSitePlus
S708 Phosphorylation PhosphoSitePlus
S830 Phosphorylation PhosphoSitePlus
Y1043 Phosphorylation PhosphoSitePlus
S1067 Phosphorylation PhosphoSitePlus
Y1119 Phosphorylation PhosphoSitePlus
Y1135 Phosphorylation PhosphoSitePlus
Y1136 Phosphorylation PhosphoSitePlus
Y1167 Phosphorylation PhosphoSitePlus
Y1172 Phosphorylation PhosphoSitePlus
T1237 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y373 Phosphorylation HPRD 17322306


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S18 P18 Biomuta DOID:3571 / liver cancer [ cosmic ]
S86 F86 Biomuta DOID:1324 / lung cancer [ cosmic ]
S212 I212 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
Y213 H213 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S311 L311 Biomuta DOID:5158 / pleural cancer [ cosmic ]
T384 I384 Biomuta DOID:363 / uterine cancer [ icgc ]
Y1119 C1119 Biomuta DOID:9256 / colorectal cancer [ cosmic ]