Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14872 / MTF1_HUMAN
Protein Name Metal regulatory transcription factor 1
Gene Name Name: MTF1
Organism Homo sapiens (Human)

PRO ID PR:Q14872
DAG View
PRO Name metal regulatory transcription factor 1 (human)
Definition A metal regulatory transcription factor 1 that is encoded in the genome of human.
Short Label hMTF1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14872 (MTF1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S5 Phosphorylation PhosphoSitePlus
S39 Phosphorylation PhosphoSitePlus
K133 Ubiquitination PhosphoSitePlus
Y140 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 11923282
Y151 Phosphorylation PhosphoSitePlus
S152 Phosphorylation PhosphoSitePlus
K227 Acetylation PhosphoSitePlus
T252 Phosphorylation PhosphoSitePlus
T254 Phosphorylation PhosphoSitePlus
K257 Ubiquitination PhosphoSitePlus
K277 Ubiquitination PhosphoSitePlus
T284 Phosphorylation PhosphoSitePlus
S293 Phosphorylation PhosphoSitePlus
S305 Phosphorylation PhosphoSitePlus   UniProt 23186163
K307 Methylation PhosphoSitePlus
S620 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K227 E227 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
T254 K254 Biomuta DOID:3277 / thymus cancer [ tcga ]
T254 I254 Biomuta DOID:1115 / sarcoma [ tcga ]
T284 N284 Biomuta DOID:3571 / liver cancer [ icgc ]
S305 G305 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
K307 E307 Biomuta DOID:1324 / lung cancer [ tcga ]