Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14831 / GRM7_HUMAN
Protein Name Metabotropic glutamate receptor 7 precursor
Gene Name Name: GRM7
Synonyms:GPRC1G,MGLUR7;
Organism Homo sapiens (Human)

PRO ID PR:Q14831
DAG View
PRO Name metabotropic glutamate receptor 7 (human)
Definition A metabotropic glutamate receptor 7 that is encoded in the genome of human.
Short Label hGRM7
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14831 (GRM7) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T12 Phosphorylation PhosphoSitePlus
T223 Phosphorylation PhosphoSitePlus
S226 Phosphorylation PhosphoSitePlus
S229 Phosphorylation PhosphoSitePlus
T264 Phosphorylation PhosphoSitePlus
T386 Phosphorylation PhosphoSitePlus
T675 Phosphorylation PhosphoSitePlus
T677 Phosphorylation PhosphoSitePlus
T822 Phosphorylation PhosphoSitePlus
S862 Phosphorylation PhosphoSitePlus   RLIMS-P 12021391
S874 Phosphorylation PhosphoSitePlus
K889 Sumoylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T264 Phosphorylation HPRD 19664994
T675 Phosphorylation HPRD 18491316
T677 Phosphorylation HPRD 18491316
Site PTM Type PTM Enzyme Score Source PMID
T264 Phosphorylation HPRD 19664994
T675 Phosphorylation HPRD 18491316
T677 Phosphorylation HPRD 18491316


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T223 I223 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S226 * Biomuta DOID:5041 / esophageal cancer [ tcga ]
S226 L226 Biomuta DOID:1909 / melanoma [ tcga ]
S229 T229 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
T264 I264 Biomuta DOID:363 / uterine cancer [ icgc, tcga ]
T386 K386 Biomuta DOID:1324 / lung cancer [ tcga ]
T675 M675 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ tcga ] DOID:11934 / head and neck cancer [ tcga ]
T677 R677 Biomuta DOID:1324 / lung cancer [ cosmic ]
S874 L874 Biomuta DOID:1909 / melanoma [ tcga ]