iPTMnet Report for Q14781 (CBX2)
Protein Information
| UniProt AC / UniProt ID | Q14781 / CBX2_HUMAN |
| Protein Name | Chromobox protein homolog 2 |
| Gene Name | Name: CBX2 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q14781 |
| PRO Name | chromobox protein homolog 2 (human) |
| Definition | A chromobox protein homolog 2 that is encoded in the genome of human. |
| Short Label | hCBX2 |
| Category | organism-gene |
Q14781 (CBX2) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| C16 | Methylation | score1 | IEDB | 31844290 | ||
| K60 | Sumoylation | score1 | PhosphoSitePlus | |||
| T84 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S87 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K96 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S102 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S104 | O-Glycosylation | score1 | GlyGen | 30379171 | ||
| S104 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S107 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S120 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S126 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K146 | Sumoylation | score1 | PhosphoSitePlus | |||
| K153 | Sumoylation | score1 | PhosphoSitePlus | |||
| S181 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K184 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K191 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K199 | Acetylation | score1 | PhosphoSitePlus | |||
| S205 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K215 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K219 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T230 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R247 | Methylation | score2 | PhosphoSitePlus UniProt | 24129315 | ||
| Y259 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K277 | Methylation | score1 | PhosphoSitePlus | |||
| K277 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T281 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K283 | Methylation | score1 | PhosphoSitePlus | |||
| K283 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K291 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T294 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S302 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| K310 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K320 | Sumoylation | score1 | PhosphoSitePlus | |||
| K320 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K379 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K390 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K410 | Sumoylation | score1 | PhosphoSitePlus | |||
| T423 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K427 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K432 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S434 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T436 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S438 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S520 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| C16 | F16 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| K96 | N96 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
| S104 | F104 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S120 | * | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
| K184 | N184 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| K191 | E191 | Biomuta | DOID:9253 / gastrointestinal stromal tumor [ cosmic ] | |
| R247 | W247 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
| R247 | L247 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| K277 | * | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
| T281 | A281 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| T294 | M294 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] | |
| K379 | * | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| K379 | N379 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| K427 | M427 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |
DAG View