Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14767 / LTBP2_HUMAN
Protein Name Latent-transforming growth factor beta-binding protein 2 precursor
Gene Name Name: LTBP2
Synonyms:C14orf141,LTBP3;
Organism Homo sapiens (Human)

PRO ID PR:Q14767
DAG View
PRO Name latent-transforming growth factor beta-binding protein 2 (human)
Definition A latent-transforming growth factor beta-binding protein 2 that is encoded in the genome of human.
Short Label hLTBP2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14767 (LTBP2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S59 Phosphorylation PhosphoSitePlus
Y60 Phosphorylation PhosphoSitePlus
T147 Phosphorylation PhosphoSitePlus
S151 Phosphorylation PhosphoSitePlus
N181 N-Glycosylation GlyGen 23090970, 24190977
S250 Phosphorylation PhosphoSitePlus
S267 O-Glycosylation GlyGen 30459171
S273 O-Glycosylation GlyGen 30459171
T278 O-Glycosylation GlyGen 30459171
T285 O-Glycosylation GlyGen 30459171, 25813380
S288 O-Glycosylation GlyGen 30459171, 25813380
T303 O-Glycosylation GlyGen 30459171
T305 O-Glycosylation GlyGen 30459171
S308 O-Glycosylation GlyGen 30459171
S311 O-Glycosylation GlyGen 30459171
S312 O-Glycosylation GlyGen 30459171
N343 N-Glycosylation GlyGen 23090970, 29741879, 24190977
S372 Phosphorylation PhosphoSitePlus
T380 O-Glycosylation GlyGen 30459171
N421 N-Glycosylation GlyGen 23090970, 29741879, 24190977
S468 O-Glycosylation GlyGen 30459171
S506 Phosphorylation PhosphoSitePlus
T509 O-Glycosylation GlyGen 30459171
S518 O-Glycosylation GlyGen 30459171
N616 N-Glycosylation GlyGen 29741879
T682 Phosphorylation PhosphoSitePlus
T731 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T777 O-Glycosylation GlyGen 25813380
T802 O-Glycosylation GlyGen 30459171
T813 O-Glycosylation GlyGen 30459171
T831 O-Glycosylation GlyGen 30459171
T839 O-Glycosylation GlyGen 30459171
T1026 Phosphorylation PhosphoSitePlus
S1031 Phosphorylation PhosphoSitePlus
S1395 Phosphorylation PhosphoSitePlus
S1397 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T1401 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171
Y1414 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S250 N250 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S267 L267 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S273 L273 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T278 N278 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S288 F288 Biomuta DOID:4159 / skin cancer [ cosmic ]
S312 F312 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
N343 T343 Biomuta DOID:10283 / prostate cancer [ icgc ]
T380 P380 Biomuta DOID:1612 / breast cancer [ cosmic ]
S506 R506 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S518 I518 Biomuta [ cosmic ]
T777 M777 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S1031 F1031 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1395 G1395 Biomuta DOID:1324 / lung cancer [ cosmic ]