iPTMnet Report for Q14767 (LTBP2)
Protein Information
| UniProt AC / UniProt ID | Q14767 / LTBP2_HUMAN |
| Protein Name | Latent-transforming growth factor beta-binding protein 2 precursor |
| Gene Name | Name: LTBP2 Synonyms:C14orf141,LTBP3; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q14767 |
| PRO Name | latent-transforming growth factor beta-binding protein 2 (human) |
| Definition | A latent-transforming growth factor beta-binding protein 2 that is encoded in the genome of human. |
| Short Label | hLTBP2 |
| Category | organism-gene |
Q14767 (LTBP2) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S59 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y60 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T147 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S151 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N181 | N-Glycosylation | score1 | GlyGen | 23090970, 24190977 | ||
| S250 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S267 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| S273 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| T278 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| T285 | O-Glycosylation | score1 | GlyGen | 30459171, 25813380 | ||
| S288 | O-Glycosylation | score1 | GlyGen | 30459171, 25813380 | ||
| T303 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| T305 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| S308 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| S311 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| S312 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| N343 | N-Glycosylation | score1 | GlyGen | 23090970, 29741879, 24190977 | ||
| S372 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T380 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| N421 | N-Glycosylation | score1 | GlyGen | 23090970, 29741879, 24190977 | ||
| S468 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| S506 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T509 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| S518 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| N616 | N-Glycosylation | score1 | GlyGen | 29741879 | ||
| T682 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T731 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
| T777 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
| T802 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| T813 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| T831 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| T839 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| T1026 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1031 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1395 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1397 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
| T1401 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 30459171 | ||
| Y1414 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S250 | N250 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| S267 | L267 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S273 | L273 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
| T278 | N278 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| S288 | F288 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S312 | F312 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| N343 | T343 | Biomuta | DOID:10283 / prostate cancer [ icgc ] | |
| T380 | P380 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
| S506 | R506 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] | |
| S518 | I518 | Biomuta | [ cosmic ] | |
| T777 | M777 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S1031 | F1031 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S1395 | G1395 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |
DAG View