iPTMnet Report for Q14746 (COG2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14746 / COG2_HUMAN
Protein Name Conserved oligomeric Golgi complex subunit 2
Gene Name Name: COG2
Synonyms:LDLC;
Organism Homo sapiens (Human)

PRO ID PR:Q14746
DAG View
PRO Name conserved oligomeric Golgi complex subunit 2 (human)
Definition A conserved oligomeric Golgi complex subunit 2 that is encoded in the genome of human.
Short Label hCOG2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14746 (COG2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R5 Methylation PhosphoSitePlus
K19 Ubiquitination PhosphoSitePlus
K24 Ubiquitination PhosphoSitePlus
Y52 Phosphorylation PhosphoSitePlus
K54 Ubiquitination PhosphoSitePlus
K57 Ubiquitination PhosphoSitePlus
S104 Phosphorylation PhosphoSitePlus
S118 Phosphorylation PhosphoSitePlus
K119 Ubiquitination PhosphoSitePlus
K145 Ubiquitination PhosphoSitePlus
K153 Ubiquitination PhosphoSitePlus
S162 Phosphorylation PhosphoSitePlus
K188 Ubiquitination PhosphoSitePlus
K195 Ubiquitination PhosphoSitePlus
K239 Ubiquitination PhosphoSitePlus
S375 Phosphorylation PhosphoSitePlus
K378 Ubiquitination PhosphoSitePlus
K379 Ubiquitination PhosphoSitePlus
K475 Ubiquitination PhosphoSitePlus
K476 Ubiquitination PhosphoSitePlus
K503 Ubiquitination PhosphoSitePlus
K535 Ubiquitination PhosphoSitePlus
K584 Methylation PhosphoSitePlus
K584 Ubiquitination PhosphoSitePlus
K598 Ubiquitination PhosphoSitePlus
K613 Ubiquitination PhosphoSitePlus
K627 Ubiquitination PhosphoSitePlus
S656 Phosphorylation PhosphoSitePlus
K658 Ubiquitination PhosphoSitePlus
K668 Acetylation PhosphoSitePlus
K672 Ubiquitination PhosphoSitePlus
S686 Phosphorylation PhosphoSitePlus
K690 Ubiquitination PhosphoSitePlus
K717 Ubiquitination PhosphoSitePlus
K730 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y52 Phosphorylation HPRD 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S104 L104 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
K145 N145 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S162 G162 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K476 R476 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K503 N503 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K627 Q627 Biomuta DOID:10283 / prostate cancer [ cosmic ]
K730 R730 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]