iPTMnet Report for Q14703 (MBTPS1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14703 / MBTP1_HUMAN
Protein Name Membrane-bound transcription factor site-1 protease precursor
Gene Name Name: MBTPS1
Synonyms:KIAA0091;
Organism Homo sapiens (Human)

PRO ID PR:Q14703
DAG View
PRO Name membrane-bound transcription factor site-1 protease (human)
Definition A membrane-bound transcription factor site-1 protease that is encoded in the genome of human.
Short Label hMBTPS1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14703 (MBTPS1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K78 Ubiquitination PhosphoSitePlus
K107 Ubiquitination PhosphoSitePlus
K137 Ubiquitination PhosphoSitePlus
N148 N-Glycosylation GlyGen 23090970, 29741879, 24190977
S166 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S168 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S168 Phosphorylation UniProt 26091039
T177 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T177 Phosphorylation PhosphoSitePlus
R213 Methylation PhosphoSitePlus
K224 Ubiquitination PhosphoSitePlus
K229 Ubiquitination PhosphoSitePlus
T235 Phosphorylation PhosphoSitePlus
K388 Ubiquitination PhosphoSitePlus
S417 Phosphorylation PhosphoSitePlus
S429 Phosphorylation PhosphoSitePlus
T430 Phosphorylation IEDB 35494241
K443 Ubiquitination PhosphoSitePlus
T616 Phosphorylation PhosphoSitePlus
K646 Ubiquitination PhosphoSitePlus
T896 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
K934 Ubiquitination PhosphoSitePlus
N939 N-Glycosylation GlyGen 23090970, 24190977
K951 Ubiquitination PhosphoSitePlus
K1036 Acetylation PhosphoSitePlus
K1048 Acetylation PhosphoSitePlus
T1049 Phosphorylation PhosphoSitePlus
S1051 Phosphorylation HPRD   PhosphoSitePlus 18491316


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K78 * Biomuta DOID:263 / kidney cancer [ cosmic ]
N148 S148 Biomuta DOID:3571 / liver cancer [ cosmic ]
K951 N951 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K951 R951 Biomuta DOID:263 / kidney cancer [ cosmic ]