iPTMnet Report for Q14699 (RFTN1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14699 / RFTN1_HUMAN
Protein Name Raftlin
Gene Name Name: RFTN1
Synonyms:KIAA0084;ORFNames:MIG2;
Organism Homo sapiens (Human)

PRO ID PR:Q14699
DAG View
PRO Name raftlin (human)
Definition A raftlin that is encoded in the genome of human.
Short Label hRFTN1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14699 (RFTN1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
G2 Myristoylation UniProt 12805216, 20213681
K14 Ubiquitination PhosphoSitePlus
Y20 Phosphorylation PhosphoSitePlus
S21 O-Glycosylation GlyGen 30620550
S21 Phosphorylation PhosphoSitePlus
Y36 Phosphorylation PhosphoSitePlus
K114 Ubiquitination PhosphoSitePlus
Y122 Phosphorylation PhosphoSitePlus
K139 Ubiquitination PhosphoSitePlus
K146 Ubiquitination PhosphoSitePlus
K147 Ubiquitination PhosphoSitePlus
S153 Phosphorylation IEDB 35494241
S171 Phosphorylation PhosphoSitePlus
T180 Phosphorylation PhosphoSitePlus
S199 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17081983, 24275569
K204 Ubiquitination PhosphoSitePlus
C211 S-Nitrosylation dbSNO 22178444
S220 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983
K235 Ubiquitination PhosphoSitePlus
S238 Phosphorylation PhosphoSitePlus
S239 Phosphorylation HPRD   PhosphoSitePlus 18578522
S241 Phosphorylation PhosphoSitePlus
S250 Phosphorylation PhosphoSitePlus
K276 Ubiquitination PhosphoSitePlus
K424 Ubiquitination PhosphoSitePlus
K437 Ubiquitination PhosphoSitePlus
K444 Ubiquitination PhosphoSitePlus
S450 Phosphorylation PhosphoSitePlus
S462 Phosphorylation PhosphoSitePlus
S467 Phosphorylation PhosphoSitePlus
K479 Ubiquitination PhosphoSitePlus
S486 Phosphorylation PhosphoSitePlus
S505 Phosphorylation PhosphoSitePlus
K516 Ubiquitination PhosphoSitePlus
S555 Phosphorylation HPRD   PhosphoSitePlus 18578522


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K14 Q14 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S21 * Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ]
K146 N146 Biomuta DOID:9256 / colorectal cancer [ icgc ]
T180 N180 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S239 L239 Biomuta DOID:4159 / skin cancer [ cosmic ]
S239 P239 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S250 * Biomuta DOID:1612 / breast cancer [ cosmic ]
S250 L250 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S467 G467 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]