iPTMnet Report for Q14696 (MESD)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14696 / MESD_HUMAN
Protein Name LRP chaperone MESD precursor
Gene Name Name: MESD
Synonyms:KIAA0081,MESDC2,MESDM;ORFNames:UNQ1911/PRO4369;
Organism Homo sapiens (Human)

PRO ID PR:Q14696
DAG View
PRO Name LRP chaperone MESD (human)
Definition A mesoderm development candidate 2 that is encoded in the genome of human.
Short Label hMESD
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14696 (MESD) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C32 Methylation IEDB 31844290
Y58 Phosphorylation PhosphoSitePlus
K72 Ubiquitination PhosphoSitePlus
K85 Ubiquitination PhosphoSitePlus
S88 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S88 Phosphorylation PhosphoSitePlus
K95 Methylation PhosphoSitePlus
T113 Phosphorylation PhosphoSitePlus
S121 Phosphorylation PhosphoSitePlus
S123 Phosphorylation PhosphoSitePlus
T125 Phosphorylation PhosphoSitePlus
R179 Methylation PhosphoSitePlus
K207 Ubiquitination PhosphoSitePlus
K209 Ubiquitination PhosphoSitePlus
K210 Ubiquitination PhosphoSitePlus
K211 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K95 M95 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K95 T95 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T125 A125 Biomuta DOID:9256 / colorectal cancer [ cosmic ]