iPTMnet Report for Q14693 (LPIN1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14693 / LPIN1_HUMAN
Protein Name Phosphatidate phosphatase LPIN1
Gene Name Name: LPIN1
Synonyms:KIAA0188;
Organism Homo sapiens (Human)

PRO ID PR:Q14693
DAG View
PRO Name phosphatidate phosphatase LPIN1 (human)
Definition A phosphatidate phosphatase LPIN1 that is encoded in the genome of human.
Short Label hLPIN1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14693 (LPIN1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T14 Phosphorylation PhosphoSitePlus
K54 Ubiquitination PhosphoSitePlus
S106 Phosphorylation P42345 (MTOR) neXtProt   phospho.ELM   PRO 21816276, 18669648
S134 Phosphorylation PhosphoSitePlus
T135 Phosphorylation PhosphoSitePlus
T145 Phosphorylation PhosphoSitePlus
S148 Phosphorylation PhosphoSitePlus
S162 Phosphorylation IEDB   PhosphoSitePlus 27869121
S166 Phosphorylation PhosphoSitePlus
T175 Phosphorylation PhosphoSitePlus
S176 Phosphorylation PhosphoSitePlus
S187 Phosphorylation PhosphoSitePlus
S188 Phosphorylation PhosphoSitePlus
S248 Phosphorylation IEDB 30784271
T249 Phosphorylation IEDB   PhosphoSitePlus 11120772
S252 Phosphorylation PhosphoSitePlus
S254 Phosphorylation PhosphoSitePlus
S286 Phosphorylation PhosphoSitePlus
S293 Phosphorylation PhosphoSitePlus
S294 Phosphorylation PhosphoSitePlus
S297 Phosphorylation PhosphoSitePlus
Y398 Phosphorylation PhosphoSitePlus   RLIMS-P 33203880
Y413 Phosphorylation PhosphoSitePlus   RLIMS-P 33203880
K425 Acetylation UniProt 29765047
S434 Phosphorylation PhosphoSitePlus
S438 Phosphorylation P42345 (MTOR) neXtProt   PhosphoSitePlus 21816276
S449 Phosphorylation PhosphoSitePlus
T479 Phosphorylation PhosphoSitePlus
K480 Ubiquitination PhosphoSitePlus
T563 Phosphorylation PhosphoSitePlus
S580 Phosphorylation PhosphoSitePlus
K595 Acetylation UniProt 29765047
K609 Ubiquitination PhosphoSitePlus
K636 Ubiquitination PhosphoSitePlus
K698 Ubiquitination PhosphoSitePlus
K707 Ubiquitination PhosphoSitePlus
K711 Ubiquitination PhosphoSitePlus
S713 Phosphorylation PhosphoSitePlus
Y717 Phosphorylation PhosphoSitePlus
K770 Ubiquitination PhosphoSitePlus
K776 Ubiquitination PhosphoSitePlus
Y795 Phosphorylation PhosphoSitePlus   RLIMS-P 33203880
K854 Ubiquitination PhosphoSitePlus
S887 Phosphorylation PhosphoSitePlus
S889 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S106 Phosphorylation HPRD 18669648
S252 Phosphorylation HPRD 19651622
Site PTM Type PTM Enzyme Score Source PMID
S237 Phosphorylation PhosphoSitePlus
S264 Phosphorylation PhosphoSitePlus
S269 Phosphorylation PhosphoSitePlus
S270 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S243 Phosphorylation PhosphoSitePlus
S270 Phosphorylation PhosphoSitePlus
S275 Phosphorylation PhosphoSitePlus
S276 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S243 Phosphorylation PhosphoSitePlus
S270 Phosphorylation PhosphoSitePlus
S275 Phosphorylation PhosphoSitePlus
S276 Phosphorylation PhosphoSitePlus


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000048236 (hLPIN1/Phos:1) pS106 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T14 I14 Biomuta DOID:4159 / skin cancer [ cosmic ]
T135 M135 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ cosmic ]
S252 R252 Biomuta DOID:363 / uterine cancer [ icgc ]
T563 I563 Biomuta DOID:263 / kidney cancer [ cosmic ]
S580 N580 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K595 N595 Biomuta DOID:1324 / lung cancer [ cosmic ]
K609 R609 Biomuta DOID:363 / uterine cancer [ icgc ]
Y717 H717 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K770 N770 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
Y795 H795 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S887 C887 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
S889 L889 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]