Protein Information

Cytoscape View

UniProt AC / UniProt ID Q14691 / PSF1_HUMAN
Protein Name DNA replication complex GINS protein PSF1
Gene Name Name: GINS1
Organism Homo sapiens (Human)

PRO ID PR:Q14691
DAG View
PRO Name DNA replication complex GINS protein PSF1 (human)
Definition A DNA replication complex GINS protein PSF1 that is encoded in the genome of human.
Short Label hGINS1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q14691 (GINS1) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
K5 Ubiquitination PhosphoSitePlus
K37 Ubiquitination PhosphoSitePlus
Y40 Phosphorylation PhosphoSitePlus
S45 Phosphorylation PhosphoSitePlus
K51 Ubiquitination PhosphoSitePlus
S52 Phosphorylation PhosphoSitePlus
S56 Phosphorylation PhosphoSitePlus
K63 Acetylation PhosphoSitePlus
K63 Ubiquitination PhosphoSitePlus
K141 Ubiquitination PhosphoSitePlus
Y156 Phosphorylation PhosphoSitePlus
T165 Phosphorylation PhosphoSitePlus
S166 Phosphorylation PhosphoSitePlus
K170 Ubiquitination PhosphoSitePlus
K171 Ubiquitination PhosphoSitePlus
K181 Ubiquitination PhosphoSitePlus
S196 Phosphorylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S45 F45 Biomuta DOID:1324 / lung cancer [ tcga ]
K51 N51 Biomuta DOID:3571 / liver cancer [ icgc ]
K171 I171 Biomuta DOID:363 / uterine cancer [ tcga ]
S196 * Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]