iPTMnet Report for Q14691 (GINS1)
Protein Information
UniProt AC / UniProt ID | Q14691 / PSF1_HUMAN |
Protein Name | DNA replication complex GINS protein PSF1 |
Gene Name | Name: GINS1 Synonyms:KIAA0186,PSF1; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q14691 |
PRO Name | DNA replication complex GINS protein PSF1 (human) |
Definition | A DNA replication complex GINS protein PSF1 that is encoded in the genome of human. |
Short Label | hGINS1 |
Category | organism-gene |
Q14691 (GINS1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
C3 | Methylation | score1 | IEDB | 31844290 | ||
K5 | Ubiquitination | score1 | PhosphoSitePlus | |||
K37 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y40 | Phosphorylation | score1 | PhosphoSitePlus | |||
S45 | Phosphorylation | score1 | PhosphoSitePlus | |||
K51 | Ubiquitination | score1 | PhosphoSitePlus | |||
S52 | Phosphorylation | score1 | PhosphoSitePlus | |||
S56 | Phosphorylation | score1 | PhosphoSitePlus | |||
K63 | Acetylation | score1 | PhosphoSitePlus | |||
K63 | Ubiquitination | score1 | PhosphoSitePlus | |||
K141 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y156 | Phosphorylation | score1 | PhosphoSitePlus | |||
T165 | Phosphorylation | score1 | PhosphoSitePlus | |||
S166 | Phosphorylation | score1 | PhosphoSitePlus | |||
K170 | Ubiquitination | score1 | PhosphoSitePlus | |||
K171 | Ubiquitination | score1 | PhosphoSitePlus | |||
K181 | Ubiquitination | score1 | PhosphoSitePlus | |||
S196 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S45 | F45 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
K171 | I171 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S196 | * | Biomuta | DOID:1612 / breast cancer [ cosmic ] |