iPTMnet Report for Q14678 (KANK1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14678 / KANK1_HUMAN
Protein Name KN motif and ankyrin repeat domain-containing protein 1
Gene Name Name: KANK1
Synonyms:ANKRD15,KANK,KIAA0172;
Organism Homo sapiens (Human)

PRO ID PR:Q14678
DAG View
PRO Name KN motif and ankyrin repeat domain-containing protein 1 (human)
Definition A KN motif and ankyrin repeat domain-containing protein 1 that is encoded in the genome of human.
Short Label hKANK1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14678 (KANK1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S20 Phosphorylation PhosphoSitePlus
K54 Ubiquitination PhosphoSitePlus
S70 Phosphorylation PhosphoSitePlus
T116 Phosphorylation PhosphoSitePlus
S128 Phosphorylation PhosphoSitePlus
T133 Phosphorylation PhosphoSitePlus
S144 Phosphorylation PhosphoSitePlus
T175 Phosphorylation PhosphoSitePlus
S186 Phosphorylation PhosphoSitePlus   UniProt 24275569
S194 Phosphorylation PhosphoSitePlus
S242 Phosphorylation PhosphoSitePlus
S256 Phosphorylation PhosphoSitePlus
T283 Phosphorylation PhosphoSitePlus
K306 Ubiquitination PhosphoSitePlus
S312 Phosphorylation PhosphoSitePlus
S323 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Y324 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S325 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 18458160, ...18669648, 19690332
S330 Phosphorylation PhosphoSitePlus
S341 Phosphorylation PhosphoSitePlus
T429 Phosphorylation PhosphoSitePlus
K466 Ubiquitination PhosphoSitePlus
T479 Phosphorylation PhosphoSitePlus
T480 Phosphorylation PhosphoSitePlus
S497 O-Glycosylation GlyGen 30379171
T505 O-Glycosylation GlyGen 30379171
T505 Phosphorylation PhosphoSitePlus
S513 Phosphorylation PhosphoSitePlus
T522 Phosphorylation PhosphoSitePlus
S529 Phosphorylation PhosphoSitePlus
T544 Phosphorylation PhosphoSitePlus
S546 Phosphorylation PhosphoSitePlus
S585 Phosphorylation PhosphoSitePlus
S592 Phosphorylation PhosphoSitePlus
T709 O-Glycosylation GlyGen 30379171
T756 Phosphorylation PhosphoSitePlus
Y770 Phosphorylation PhosphoSitePlus
S796 Phosphorylation PhosphoSitePlus
S879 Phosphorylation PhosphoSitePlus
S881 Phosphorylation PhosphoSitePlus
T882 Phosphorylation PhosphoSitePlus
K892 Ubiquitination PhosphoSitePlus
K1088 Ubiquitination PhosphoSitePlus
K1104 Ubiquitination PhosphoSitePlus
S1331 Phosphorylation PhosphoSitePlus
T1334 Phosphorylation PhosphoSitePlus
T1341 Phosphorylation PhosphoSitePlus
S1342 Phosphorylation PhosphoSitePlus
T1346 Phosphorylation PhosphoSitePlus
S1350 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S323 Phosphorylation HPRD 20166139, 18669648, 19664995, ...20068231, 19691289
Y324 Phosphorylation HPRD 18669648
S325 Phosphorylation HPRD 20166139, 18669648, 19664994, ...19664995, 20068231
S879 Phosphorylation HPRD 20166139
S881 Phosphorylation HPRD 20166139
Site PTM Type PTM Enzyme Score Source PMID
S165 Phosphorylation HPRD 20166139, 18669648, 19664995, ...20068231, 19691289
Y166 Phosphorylation HPRD 18669648
S167 Phosphorylation HPRD 20166139, 18669648, 19664994, ...19664995, 20068231
S721 Phosphorylation HPRD 20166139
S723 Phosphorylation HPRD 20166139


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K54 N54 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S70 F70 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S186 N186 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S194 R194 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T283 A283 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T480 S480 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S497 L497 Biomuta DOID:4159 / skin cancer [ cosmic ]
T505 M505 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S529 R529 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
Y770 H770 Biomuta DOID:3571 / liver cancer [ cosmic ]
T1341 M1341 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S1342 Y1342 Biomuta DOID:263 / kidney cancer [ cosmic ]
S1350 L1350 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]