iPTMnet Report for Q14596 (NBR1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14596 / NBR1_HUMAN
Protein Name Next to BRCA1 gene 1 protein
Gene Name Name: NBR1
Synonyms:1A13B,KIAA0049,M17S2;ORFNames:MIG19;
Organism Homo sapiens (Human)

PRO ID PR:Q14596
DAG View
PRO Name next to BRCA1 gene 1 protein (human)
Definition A next to BRCA1 gene 1 protein that is encoded in the genome of human.
Short Label hNBR1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14596 (NBR1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S60 Phosphorylation PhosphoSitePlus
K100 Ubiquitination PhosphoSitePlus
K108 Ubiquitination PhosphoSitePlus
K109 Ubiquitination PhosphoSitePlus
S115 Phosphorylation PhosphoSitePlus
S116 Phosphorylation IEDB   PhosphoSitePlus   UniProt 35494241, 23186163
K126 Ubiquitination PhosphoSitePlus
K149 Sumoylation PhosphoSitePlus
K149 Ubiquitination PhosphoSitePlus
K172 Ubiquitination PhosphoSitePlus
K176 Ubiquitination PhosphoSitePlus
K274 Ubiquitination PhosphoSitePlus
S276 Phosphorylation PhosphoSitePlus
T277 Phosphorylation PhosphoSitePlus
K291 Ubiquitination PhosphoSitePlus
K295 Ubiquitination PhosphoSitePlus
K299 Ubiquitination PhosphoSitePlus
K313 Acetylation PhosphoSitePlus
K317 Ubiquitination PhosphoSitePlus
K320 Ubiquitination PhosphoSitePlus
K328 Ubiquitination PhosphoSitePlus
S334 Phosphorylation PhosphoSitePlus
S340 Phosphorylation PhosphoSitePlus
K394 Ubiquitination PhosphoSitePlus
K399 Ubiquitination PhosphoSitePlus
K405 Ubiquitination PhosphoSitePlus
K411 Ubiquitination PhosphoSitePlus
K426 Ubiquitination PhosphoSitePlus
K427 Ubiquitination PhosphoSitePlus
K464 Ubiquitination PhosphoSitePlus
S486 Phosphorylation PhosphoSitePlus
K492 Ubiquitination PhosphoSitePlus
K499 Ubiquitination PhosphoSitePlus
K515 Ubiquitination PhosphoSitePlus
C533 Methylation IEDB 31844290
K537 Ubiquitination PhosphoSitePlus
K539 Ubiquitination PhosphoSitePlus
T581 Phosphorylation PhosphoSitePlus
T586 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 24879152
S590 Phosphorylation PhosphoSitePlus   RLIMS-P 24879152
S596 Phosphorylation PhosphoSitePlus
K601 Ubiquitination PhosphoSitePlus
K617 Ubiquitination PhosphoSitePlus
S622 Phosphorylation PhosphoSitePlus
S625 Phosphorylation PhosphoSitePlus   UniProt 23186163
K627 Ubiquitination PhosphoSitePlus
K629 Ubiquitination PhosphoSitePlus
S656 Phosphorylation PhosphoSitePlus
T658 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
K672 Ubiquitination PhosphoSitePlus
S673 Phosphorylation PhosphoSitePlus
K767 Ubiquitination PhosphoSitePlus
S824 Phosphorylation PhosphoSitePlus
S825 Phosphorylation PhosphoSitePlus
S833 Phosphorylation PhosphoSitePlus
K887 Ubiquitination PhosphoSitePlus
K898 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T277 Phosphorylation HPRD 20068231
S334 Phosphorylation HPRD 20068231
S673 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S60 N60 Biomuta DOID:4159 / skin cancer [ cosmic ]
K108 R108 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K274 E274 Biomuta DOID:4159 / skin cancer [ cosmic ]
S276 C276 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K295 N295 Biomuta DOID:363 / uterine cancer [ icgc ]
K317 N317 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K426 N426 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
K427 N427 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T586 I586 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T658 I658 Biomuta DOID:4159 / skin cancer [ cosmic ]
S825 Y825 Biomuta DOID:363 / uterine cancer [ icgc ]
S833 F833 Biomuta DOID:4159 / skin cancer [ cosmic ]
K898 N898 Biomuta DOID:3571 / liver cancer [ cosmic ]