iPTMnet Report for Q14533 (KRT81)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14533 / KRT81_HUMAN
Protein Name Keratin, type II cuticular Hb1
Gene Name Name: KRT81
Synonyms:KRTHB1,MLN137;
Organism Homo sapiens (Human)

PRO ID PR:Q14533
DAG View
PRO Name keratin, type II cuticular Hb1 (human)
Definition A keratin, type II cuticular Hb1 that is encoded in the genome of human.
Short Label hKRT81
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14533 (KRT81) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S47 Phosphorylation PhosphoSitePlus
S49 Phosphorylation PhosphoSitePlus
K132 Acetylation PhosphoSitePlus
K132 Ubiquitination PhosphoSitePlus
T203 Phosphorylation PhosphoSitePlus
S252 Phosphorylation PhosphoSitePlus
S258 Phosphorylation PhosphoSitePlus
Y282 Phosphorylation PhosphoSitePlus
Y297 Phosphorylation PhosphoSitePlus
K300 Ubiquitination PhosphoSitePlus
K305 Ubiquitination PhosphoSitePlus
T307 Phosphorylation PhosphoSitePlus
T314 Phosphorylation PhosphoSitePlus
T318 Phosphorylation PhosphoSitePlus
K319 Ubiquitination PhosphoSitePlus
K340 Ubiquitination PhosphoSitePlus
K345 Acetylation PhosphoSitePlus
K345 Ubiquitination PhosphoSitePlus
K367 Ubiquitination PhosphoSitePlus
K377 Ubiquitination PhosphoSitePlus
K379 Ubiquitination PhosphoSitePlus
Y389 Phosphorylation PhosphoSitePlus
S395 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y282 C282 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
T307 M307 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T314 I314 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K340 N340 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S395 F395 Biomuta DOID:363 / uterine cancer [ icgc ]