iPTMnet Report for Q14526 (HIC1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14526 / HIC1_HUMAN
Protein Name Hypermethylated in cancer 1 protein
Gene Name Name: HIC1
Synonyms:ZBTB29;
Organism Homo sapiens (Human)

PRO ID PR:Q14526
DAG View
PRO Name hypermethylated in cancer 1 protein (human)
Definition A hypermethylated in cancer 1 protein that is encoded in the genome of human.
Short Label hHIC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14526 (HIC1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S12 Phosphorylation PhosphoSitePlus
T19 Phosphorylation PhosphoSitePlus
S30 Phosphorylation PhosphoSitePlus
R41 Methylation PhosphoSitePlus
Y155 Phosphorylation PhosphoSitePlus
Y168 Phosphorylation PhosphoSitePlus
Y171 Phosphorylation PhosphoSitePlus
T182 Phosphorylation PhosphoSitePlus
S191 Phosphorylation PhosphoSitePlus
S232 Phosphorylation PhosphoSitePlus
S237 Phosphorylation PhosphoSitePlus   UniProt 24275569
S245 Phosphorylation PhosphoSitePlus
S248 Phosphorylation PhosphoSitePlus   UniProt 24275569
S270 Phosphorylation PhosphoSitePlus
S273 Phosphorylation PhosphoSitePlus
Y279 Phosphorylation PhosphoSitePlus
S313 Phosphorylation PhosphoSitePlus
K333 Acetylation PhosphoSitePlus   UniProt 17283066
K333 Sumoylation PhosphoSitePlus
S340 Phosphorylation PhosphoSitePlus
S351 Phosphorylation PhosphoSitePlus
S366 Phosphorylation PhosphoSitePlus   UniProt 24275569
S608 Phosphorylation PhosphoSitePlus
S704 Phosphorylation PhosphoSitePlus
S713 Phosphorylation PhosphoSitePlus
S731 Phosphorylation PhosphoSitePlus
T733 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K314 Acetylation PRO 17283066


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000028784 (hHIC1/iso:2/Ac:1) acK314 PRO 17283066


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S237 F237 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S340 N340 Biomuta DOID:10534 / stomach cancer [ icgc ]
S608 N608 Biomuta DOID:9256 / colorectal cancer [ cosmic ]