iPTMnet Report for Q14517 (FAT1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14517 / FAT1_HUMAN
Protein Name Protocadherin Fat 1 precursor
Gene Name Name: FAT1
Synonyms:CDHF7,FAT;
Organism Homo sapiens (Human)

PRO ID PR:Q14517
DAG View
PRO Name protocadherin Fat 1 (human)
Definition A protocadherin Fat 1 that is encoded in the genome of human.
Short Label hFAT1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14517 (FAT1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N40 N-Glycosylation GlyGen 23090970, 24190977
K73 Ubiquitination PhosphoSitePlus
K101 Ubiquitination PhosphoSitePlus
K121 Ubiquitination PhosphoSitePlus
K125 Ubiquitination PhosphoSitePlus
S150 Phosphorylation PhosphoSitePlus
T152 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
S153 Phosphorylation PhosphoSitePlus
S155 Phosphorylation PhosphoSitePlus
K189 Ubiquitination PhosphoSitePlus
T192 Phosphorylation HPRD 20068231
Y212 Phosphorylation HPRD 20068231
K216 Ubiquitination PhosphoSitePlus
K339 Ubiquitination PhosphoSitePlus
K341 Ubiquitination PhosphoSitePlus
S357 Phosphorylation PhosphoSitePlus
K366 Ubiquitination PhosphoSitePlus
K369 Ubiquitination PhosphoSitePlus
K390 Ubiquitination PhosphoSitePlus
K403 Ubiquitination PhosphoSitePlus
K427 Ubiquitination PhosphoSitePlus
K452 Ubiquitination PhosphoSitePlus
T464 Phosphorylation HPRD   PhosphoSitePlus 17525332
Y468 Phosphorylation HPRD   PhosphoSitePlus 17525332
Y534 Phosphorylation PhosphoSitePlus
T535 Phosphorylation PhosphoSitePlus
T558 Phosphorylation IEDB 35494241
K571 Ubiquitination PhosphoSitePlus
K686 Ubiquitination PhosphoSitePlus
K692 Ubiquitination PhosphoSitePlus
S718 O-Glycosylation GlyGen 30379171
K727 Ubiquitination PhosphoSitePlus
T771 Phosphorylation PhosphoSitePlus
S778 Phosphorylation PhosphoSitePlus
Y788 Phosphorylation PhosphoSitePlus
T789 Phosphorylation PhosphoSitePlus
T793 Phosphorylation PhosphoSitePlus
Y795 Phosphorylation PhosphoSitePlus
K894 Ubiquitination PhosphoSitePlus
K935 Ubiquitination PhosphoSitePlus
S959 Phosphorylation PhosphoSitePlus
K978 Ubiquitination PhosphoSitePlus
K993 Ubiquitination PhosphoSitePlus
N998 N-Glycosylation GlyGen 23090970, 24190977
T1000 Phosphorylation PhosphoSitePlus
K1083 Ubiquitination PhosphoSitePlus
K1173 Ubiquitination PhosphoSitePlus
Y1176 Phosphorylation PhosphoSitePlus
T1179 O-Glycosylation GlyGen 25813380
S1188 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
K1192 Ubiquitination PhosphoSitePlus
S1200 O-Glycosylation GlyGen 30379171
K1242 Ubiquitination PhosphoSitePlus
K1248 Ubiquitination PhosphoSitePlus
T1277 Phosphorylation PhosphoSitePlus
K1305 Ubiquitination PhosphoSitePlus
T1306 Phosphorylation PhosphoSitePlus
K1326 Ubiquitination PhosphoSitePlus
K1335 Ubiquitination PhosphoSitePlus
K1415 Ubiquitination PhosphoSitePlus
K1460 Ubiquitination PhosphoSitePlus
S1479 Phosphorylation IEDB 35494241
K1486 Ubiquitination PhosphoSitePlus
S1496 Phosphorylation HPRD   PhosphoSitePlus 19413330
K1503 Ubiquitination PhosphoSitePlus
K1542 Ubiquitination PhosphoSitePlus
N1551 N-Glycosylation GlyGen 23090970, 24190977
K1568 Ubiquitination PhosphoSitePlus
K1638 Ubiquitination PhosphoSitePlus
K1642 Ubiquitination PhosphoSitePlus
K1666 Ubiquitination PhosphoSitePlus
K1894 Ubiquitination PhosphoSitePlus
K1932 Ubiquitination PhosphoSitePlus
T1937 Phosphorylation PhosphoSitePlus
K1966 Ubiquitination PhosphoSitePlus
K1970 Ubiquitination PhosphoSitePlus
K1978 Ubiquitination PhosphoSitePlus
T1980 Phosphorylation PhosphoSitePlus
S1992 Phosphorylation PhosphoSitePlus
T2002 Phosphorylation PhosphoSitePlus
S2029 Phosphorylation IEDB 32387766
Y2086 Phosphorylation PhosphoSitePlus
K2138 Ubiquitination PhosphoSitePlus
K2139 Ubiquitination PhosphoSitePlus
T2410 O-Glycosylation GlyGen 25813380
K2424 Ubiquitination PhosphoSitePlus
K2553 Ubiquitination PhosphoSitePlus
K2600 Ubiquitination PhosphoSitePlus
Y2601 Phosphorylation PhosphoSitePlus
S2608 Phosphorylation PhosphoSitePlus
K2611 Ubiquitination PhosphoSitePlus
T2613 Phosphorylation PhosphoSitePlus
S2621 Phosphorylation PhosphoSitePlus
S2627 Phosphorylation PhosphoSitePlus
Y2633 Phosphorylation PhosphoSitePlus
K2643 Ubiquitination PhosphoSitePlus
K2650 Ubiquitination PhosphoSitePlus
K2683 Ubiquitination PhosphoSitePlus
T2720 Phosphorylation PhosphoSitePlus
K2739 Ubiquitination PhosphoSitePlus
K2761 Ubiquitination PhosphoSitePlus
K2764 Ubiquitination PhosphoSitePlus
K2886 Ubiquitination PhosphoSitePlus
K2981 Ubiquitination PhosphoSitePlus
K3025 Ubiquitination PhosphoSitePlus
T3048 Phosphorylation HPRD 20068231
K3069 Ubiquitination PhosphoSitePlus
K3071 Acetylation PhosphoSitePlus
K3071 Ubiquitination PhosphoSitePlus
S3082 Phosphorylation HPRD   PhosphoSitePlus 20068231
Y3253 Phosphorylation PhosphoSitePlus
K3396 Ubiquitination PhosphoSitePlus
T3402 Phosphorylation PhosphoSitePlus
S3404 Phosphorylation PhosphoSitePlus
Y3406 Phosphorylation PhosphoSitePlus
T3407 Phosphorylation PhosphoSitePlus
S3417 Phosphorylation PhosphoSitePlus
N3422 N-Glycosylation GlyGen   UniProt 19159218
K3504 Ubiquitination PhosphoSitePlus
K3522 Ubiquitination PhosphoSitePlus
K3603 Acetylation PhosphoSitePlus
N3716 N-Glycosylation GlyGen   UniProt 19159218, 19349973
K3736 Ubiquitination PhosphoSitePlus
K3746 Ubiquitination PhosphoSitePlus
K3751 Ubiquitination PhosphoSitePlus
S3757 Phosphorylation PhosphoSitePlus
S3760 O-Glycosylation GlyGen 25813380
S3760 Phosphorylation PhosphoSitePlus
T3761 O-Glycosylation GlyGen 25813380
K3783 Ubiquitination PhosphoSitePlus
K3813 Ubiquitination PhosphoSitePlus
Y3842 Phosphorylation PhosphoSitePlus
T3845 Phosphorylation PhosphoSitePlus
K3850 Ubiquitination PhosphoSitePlus
T3861 Phosphorylation PhosphoSitePlus
S3863 Phosphorylation PhosphoSitePlus
T3940 Phosphorylation PhosphoSitePlus
K3942 Ubiquitination PhosphoSitePlus
K3992 Ubiquitination PhosphoSitePlus
C4049 Methylation IEDB 31844290
K4094 Ubiquitination PhosphoSitePlus
S4207 Phosphorylation PhosphoSitePlus
K4219 Ubiquitination PhosphoSitePlus
Y4232 Phosphorylation PhosphoSitePlus
K4236 Ubiquitination PhosphoSitePlus
K4239 Ubiquitination PhosphoSitePlus
Y4242 Phosphorylation PhosphoSitePlus
S4243 Phosphorylation PhosphoSitePlus
S4255 Phosphorylation PhosphoSitePlus
S4272 Phosphorylation HPRD   PhosphoSitePlus 17081983, 20068231
S4303 Phosphorylation PhosphoSitePlus
S4316 Phosphorylation PhosphoSitePlus
S4318 Phosphorylation PhosphoSitePlus
S4322 Phosphorylation PhosphoSitePlus
S4344 Phosphorylation PhosphoSitePlus
K4351 Ubiquitination PhosphoSitePlus
S4353 Phosphorylation PhosphoSitePlus
Y4356 Phosphorylation PhosphoSitePlus
S4357 Phosphorylation PhosphoSitePlus
S4473 Phosphorylation HPRD   PhosphoSitePlus 18578522, 20068231
S4476 Phosphorylation HPRD   PhosphoSitePlus 20068231
S4477 Phosphorylation PhosphoSitePlus
Y4489 Phosphorylation PhosphoSitePlus
Y4494 Phosphorylation PhosphoSitePlus
Y4519 Phosphorylation PhosphoSitePlus
Y4523 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K73 N73 Biomuta DOID:363 / uterine cancer [ cosmic ]
T152 A152 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S153 L153 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T192 P192 Biomuta DOID:363 / uterine cancer [ icgc ]
Y212 F212 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
Y212 * Biomuta DOID:5041 / esophageal cancer [ cosmic ]
K216 N216 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
K339 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S357 Y357 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K403 * Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y468 H468 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T535 S535 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K692 T692 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S718 I718 Biomuta DOID:1324 / lung cancer [ cosmic ]
S718 N718 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T789 I789 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
Y795 C795 Biomuta DOID:5041 / esophageal cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
K935 R935 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K993 N993 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K1083 T1083 Biomuta DOID:363 / uterine cancer [ cosmic ]
Y1176 * Biomuta DOID:1324 / lung cancer [ cosmic ]
T1179 S1179 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S1188 A1188 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K1192 E1192 Biomuta DOID:4159 / skin cancer [ cosmic ]
K1192 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S1200 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K1248 R1248 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T1277 I1277 Biomuta DOID:4159 / skin cancer [ cosmic ]
K1335 T1335 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K1460 E1460 Biomuta DOID:1324 / lung cancer [ cosmic ]
K1460 * Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S1496 R1496 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
K1932 R1932 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T1937 N1937 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K1978 Q1978 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1992 F1992 Biomuta [ cosmic ] DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1115 / sarcoma [ icgc ]
Y2086 * Biomuta DOID:5041 / esophageal cancer [ cosmic ]
K2138 * Biomuta DOID:4159 / skin cancer [ cosmic ]
K2611 N2611 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S2621 N2621 Biomuta DOID:9256 / colorectal cancer [ icgc ]
Y2633 * Biomuta DOID:4159 / skin cancer [ cosmic ]
K2643 Q2643 Biomuta DOID:363 / uterine cancer [ icgc ]
K2739 Q2739 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K2764 N2764 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K2886 N2886 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
K2886 * Biomuta DOID:4159 / skin cancer [ cosmic ]
K2981 N2981 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K3396 T3396 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T3402 M3402 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S3404 * Biomuta DOID:4362 / cervical cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ]
T3407 M3407 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K3504 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K3603 N3603 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K3603 R3603 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S3760 P3760 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S3760 * Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
K3783 Q3783 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
Y3842 * Biomuta DOID:1324 / lung cancer [ cosmic ]
Y3842 S3842 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T3845 M3845 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ]
K3850 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T3861 A3861 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S3863 P3863 Biomuta DOID:1612 / breast cancer [ cosmic ]
T3940 A3940 Biomuta DOID:1319 / brain cancer [ cosmic ] DOID:2394 / ovarian cancer [ cosmic ]
K4094 I4094 Biomuta [ cosmic ]
S4207 C4207 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K4219 T4219 Biomuta [ cosmic ]
K4219 N4219 Biomuta DOID:1324 / lung cancer [ cosmic ]
K4236 E4236 Biomuta DOID:3277 / thymus cancer [ cosmic ]
S4243 * Biomuta DOID:1612 / breast cancer [ cosmic ]
S4255 F4255 Biomuta DOID:4159 / skin cancer [ cosmic ]
S4272 F4272 Biomuta DOID:4159 / skin cancer [ cosmic ]
S4303 I4303 Biomuta DOID:1324 / lung cancer [ cosmic ]
S4318 F4318 Biomuta DOID:4159 / skin cancer [ cosmic ]
S4318 Y4318 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S4322 C4322 Biomuta DOID:10283 / prostate cancer [ icgc ]
S4322 P4322 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K4351 * Biomuta DOID:4159 / skin cancer [ cosmic ]
Y4356 H4356 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y4519 S4519 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y4523 * Biomuta DOID:263 / kidney cancer [ cosmic ]