iPTMnet Report for Q14515 (SPARCL1)
Protein Information
| UniProt AC / UniProt ID | Q14515 / SPRL1_HUMAN |
| Protein Name | SPARC-like protein 1 precursor |
| Gene Name | Name: SPARCL1 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q14515 |
| PRO Name | SPARC-like protein 1 (human) |
| Definition | A SPARC-like protein 1 that is encoded in the genome of human. |
| Short Label | hSPARCL1 |
| Category | organism-gene |
DAG ViewQ14515 (SPARCL1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S25 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S28 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T31 | O-Glycosylation | score2 | GlyGen UniProt | 30459171, 23234360 | ||
| T34 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| T40 | O-Glycosylation | score2 | GlyGen UniProt | 30459171, 23234360 | ||
| S44 | O-Glycosylation | score2 | GlyGen UniProt | 30459171, 23234360 | ||
| S59 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S84 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S90 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S92 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T116 | O-Glycosylation | score2 | GlyGen UniProt | 30459171, 23234360 | ||
| S127 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T149 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| T149 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N169 | N-Glycosylation | score1 | GlyGen | 23090970 | ||
| N176 | N-Glycosylation | score1 | GlyGen | 32125861 | ||
| S182 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S198 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S231 | Phosphorylation | score2 | IEDB PhosphoSitePlus | 35494241 | ||
| S272 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S295 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T315 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| T331 | O-Glycosylation | score1 | GlyGen | 23234360 | ||
| T350 | O-Glycosylation | score1 | GlyGen | 30237853 | ||
| S356 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| S365 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| T398 | O-Glycosylation | score2 | GlyGen UniProt | 19838169, 23234360 | ||
| N412 | N-Glycosylation | score2 | GlyGen UniProt | 16335952, 23090970 | ||
| S414 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T419 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S420 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S421 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K645 | Ubiquitination | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S84 | Phosphorylation | score0 | HPRD | 18702456 | ||
| S91 | Phosphorylation | score0 | HPRD | 18702456 | ||
| S92 | Phosphorylation | score0 | HPRD | 18702456, 20187088 | ||
| S198 | Phosphorylation | score0 | HPRD | 18702456, 20187088 | ||
| S272 | Phosphorylation | score0 | HPRD | 18702456 | ||
| S295 | Phosphorylation | score0 | HPRD | 19824718, 18702456 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S25 | C25 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S59 | F59 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:1612 / breast cancer [ cosmic, icgc ] | |
| S198 | F198 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S295 | I295 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| T350 | N350 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S365 | N365 | Biomuta | DOID:1793 / pancreatic cancer [ icgc ] | |
| T419 | M419 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ] | |
| T419 | A419 | Biomuta | [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ] |
