Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14511 / CASL_HUMAN
Protein Name Enhancer of filamentation 1
Gene Name Name: NEDD9
Synonyms:CASL,CASS2;
Organism Homo sapiens (Human)

PRO ID PR:Q14511
DAG View
PRO Name enhancer of filamentation 1 (human)
Definition An enhancer of filamentation 1 that is encoded in the genome of human.
Short Label hNEDD9
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14511 (NEDD9) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y12 Phosphorylation phospho.ELM   PhosphoSitePlus 15144186
Y92 Phosphorylation PhosphoSitePlus
T104 Phosphorylation PhosphoSitePlus
Y106 Phosphorylation PhosphoSitePlus
S111 Phosphorylation PhosphoSitePlus
Y112 Phosphorylation PhosphoSitePlus
Y118 Phosphorylation PhosphoSitePlus
T122 Phosphorylation PhosphoSitePlus
T126 Phosphorylation PhosphoSitePlus
Y132 Phosphorylation PhosphoSitePlus
T160 Phosphorylation PhosphoSitePlus
Y164 Phosphorylation PhosphoSitePlus
Y166 Phosphorylation phospho.ELM   PhosphoSitePlus 12522270
Y168 Phosphorylation PhosphoSitePlus
Y172 Phosphorylation PhosphoSitePlus
Y177 Phosphorylation PhosphoSitePlus
S182 Phosphorylation PhosphoSitePlus
T184 Phosphorylation PhosphoSitePlus
T185 Phosphorylation PhosphoSitePlus
Y189 Phosphorylation PhosphoSitePlus   RLIMS-P 23874939
Y214 Phosphorylation PhosphoSitePlus
T219 Phosphorylation PhosphoSitePlus
Y223 Phosphorylation PhosphoSitePlus
S228 Phosphorylation PhosphoSitePlus
Y241 Phosphorylation PhosphoSitePlus
Y261 Phosphorylation PhosphoSitePlus
S296 Phosphorylation O14965 (AURKA) neXtProt   PhosphoSitePlus   UniProt 16184168, 19539609
S298 Phosphorylation PhosphoSitePlus
S309 Phosphorylation PhosphoSitePlus
S312 Phosphorylation PhosphoSitePlus
Y317 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
S333 Phosphorylation PhosphoSitePlus
Y345 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
S369 Phosphorylation PhosphoSitePlus   UniProt 19539609
K388 Ubiquitination PhosphoSitePlus
S395 Phosphorylation PhosphoSitePlus
K400 Ubiquitination PhosphoSitePlus
S563 Phosphorylation PhosphoSitePlus
S576 Phosphorylation PhosphoSitePlus
S616 Phosphorylation PhosphoSitePlus
S617 Phosphorylation PhosphoSitePlus
S618 Phosphorylation PhosphoSitePlus
S621 Phosphorylation PhosphoSitePlus
Y629 Phosphorylation PhosphoSitePlus
Y631 Phosphorylation PhosphoSitePlus
K650 Ubiquitination PhosphoSitePlus
S692 Phosphorylation PhosphoSitePlus
K775 Ubiquitination PhosphoSitePlus
S780 Phosphorylation PhosphoSitePlus   RLIMS-P 29191835
T804 Phosphorylation PhosphoSitePlus   RLIMS-P 29191835
Site PTM Type PTM Enzyme Score Source PMID
Y92 Phosphorylation HPRD 12522270
Y164 Phosphorylation HPRD 16497976
Y166 Phosphorylation HPRD 12522270, 15144186, 16497976
Y168 Phosphorylation HPRD 16497976
Y177 Phosphorylation HPRD 12522270
Y189 Phosphorylation HPRD 12522270
Y317 Phosphorylation HPRD 18083107
Y345 Phosphorylation HPRD 18083107
Site PTM Type PTM Enzyme Score Source PMID
Y92 Phosphorylation HPRD 12522270


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y112 N112 Biomuta DOID:363 / uterine cancer [ cosmic, tcga ]
Y168 N168 Biomuta DOID:2531 / hematologic cancer [ icgc ]
S296 R296 Biomuta DOID:3571 / liver cancer [ icgc ]
S298 F298 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S369 P369 Biomuta DOID:3070 / malignant glioma [ tcga ]
S395 F395 Biomuta DOID:0070003 / blastoma [ cosmic ]
S576 * Biomuta DOID:9256 / colorectal cancer [ icgc ]
S617 R617 Biomuta DOID:3571 / liver cancer [ icgc ]
Y629 * Biomuta DOID:3571 / liver cancer [ icgc ]
Y631 C631 Biomuta DOID:9256 / colorectal cancer [ tcga ]
S780 R780 Biomuta DOID:3571 / liver cancer [ icgc ]