iPTMnet Report for Q14444 (CAPRIN1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14444 / CAPR1_HUMAN
Protein Name Caprin-1
Gene Name Name: CAPRIN1
Synonyms:GPIAP1,GPIP137,M11S1,RNG105;
Organism Homo sapiens (Human)

PRO ID PR:Q14444
DAG View
PRO Name caprin-1 (human)
Definition A caprin-1 that is encoded in the genome of human.
Short Label hCAPRIN1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14444 (CAPRIN1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
P2 Acetylation UniProt 21406692
S6 Phosphorylation PhosphoSitePlus
S8 Phosphorylation PhosphoSitePlus
S10 Phosphorylation PhosphoSitePlus   UniProt 20068231
S12 Phosphorylation PhosphoSitePlus
S23 Phosphorylation PhosphoSitePlus
S39 Phosphorylation PhosphoSitePlus
K55 Ubiquitination PhosphoSitePlus
K63 Ubiquitination PhosphoSitePlus
K64 Ubiquitination PhosphoSitePlus
K74 Acetylation PhosphoSitePlus
K74 Methylation PhosphoSitePlus
K74 Ubiquitination PhosphoSitePlus
Y78 Phosphorylation PhosphoSitePlus
R81 Methylation PhosphoSitePlus
S97 Phosphorylation PhosphoSitePlus
K98 Ubiquitination PhosphoSitePlus
K110 Methylation PhosphoSitePlus
K110 Ubiquitination PhosphoSitePlus
S115 Phosphorylation PhosphoSitePlus   UniProt 23186163
K125 Ubiquitination PhosphoSitePlus
T126 O-Glycosylation GlyGen 23301498, 33214551, 36580660, ...20305658, 34725712, 34019948, 29351928, 35132862, 35083852, 28604694, 35138101, 22967762, 29485866, 32119511, 33465208, 35254053, 34229054
T126 Phosphorylation PhosphoSitePlus
K128 Ubiquitination PhosphoSitePlus
K129 Ubiquitination PhosphoSitePlus
K147 Ubiquitination PhosphoSitePlus
Y154 Phosphorylation PhosphoSitePlus
K158 Ubiquitination PhosphoSitePlus
K169 Ubiquitination PhosphoSitePlus
S179 Phosphorylation PhosphoSitePlus
S200 Phosphorylation PhosphoSitePlus
K221 Ubiquitination PhosphoSitePlus
K223 Ubiquitination PhosphoSitePlus
C226 Methylation IEDB 31844290
C226 S-Nitrosylation dbSNO 19483679
K231 Acetylation PhosphoSitePlus
K231 Ubiquitination PhosphoSitePlus
K234 Ubiquitination PhosphoSitePlus
S264 Phosphorylation PhosphoSitePlus
Y283 Phosphorylation PhosphoSitePlus
S287 Phosphorylation PhosphoSitePlus
T292 Phosphorylation phospho.ELM 18669648
Y294 Phosphorylation PhosphoSitePlus
S307 Phosphorylation PhosphoSitePlus
S335 Phosphorylation PhosphoSitePlus   UniProt 24275569
S337 Phosphorylation PhosphoSitePlus
S343 Phosphorylation PhosphoSitePlus   UniProt 24275569
T345 Phosphorylation PhosphoSitePlus
T384 O-Glycosylation GlyGen 23301498, 33214551, 36580660, ...20305658, 34725712, 34019948, 29351928, 35132862, 35083852, 28604694, 35138101, 22967762, 29485866, 32119511, 33465208, 35254053, 34229054
T398 Phosphorylation PhosphoSitePlus
T430 O-Glycosylation GlyGen 23301498, 33214551, 36580660, ...20305658, 34725712, 34019948, 29351928, 35132862, 35083852, 28604694, 35138101, 22967762, 29485866, 32119511, 33465208, 35254053, 34229054
S436 O-Glycosylation GlyGen 23301498, 33214551, 36580660, ...20305658, 34725712, 34019948, 29351928, 35132862, 35083852, 28604694, 35138101, 22967762, 29485866, 32119511, 33465208, 35254053, 34229054
S437 O-Glycosylation GlyGen 34846842
Y442 Phosphorylation PhosphoSitePlus
Y449 Phosphorylation PhosphoSitePlus
T470 O-Glycosylation GlyGen 28604694
S472 O-Glycosylation GlyGen 23301498, 33214551, 36580660, ...20305658, 34725712, 34019948, 29351928, 35132862, 35083852, 28604694, 35138101, 22967762, 29485866, 32119511, 33465208, 35254053, 34229054
T475 O-Glycosylation GlyGen 23301498, 33214551, 36580660, ...20305658, 34725712, 34019948, 29351928, 35132862, 35083852, 28604694, 35138101, 22967762, 29485866, 32119511, 33465208, 35254053, 34229054
T478 O-Glycosylation GlyGen 28604694
T479 O-Glycosylation GlyGen 23301498, 33214551, 36580660, ...20305658, 34725712, 34019948, 29351928, 35132862, 35083852, 28604694, 35138101, 22967762, 29485866, 32119511, 33465208, 35254053, 34229054
S481 O-Glycosylation GlyGen 23301498, 33214551, 36580660, ...20305658, 34725712, 34019948, 29351928, 35132862, 35083852, 28604694, 35138101, 22967762, 29485866, 32119511, 33465208, 35254053, 34229054
S482 O-Glycosylation GlyGen 28604694
S483 O-Glycosylation GlyGen 28604694
S488 O-Glycosylation GlyGen 23301498, 33214551, 36580660, ...20305658, 34725712, 34019948, 29351928, 35132862, 35083852, 28604694, 35138101, 22967762, 29485866, 32119511, 33465208, 35254053, 34229054
Y541 Phosphorylation PhosphoSitePlus
Y545 Phosphorylation PhosphoSitePlus
T572 Phosphorylation PhosphoSitePlus
Y573 Phosphorylation PhosphoSitePlus
R599 Methylation PhosphoSitePlus
R608 Methylation PhosphoSitePlus
S611 Phosphorylation PhosphoSitePlus
R612 Methylation PhosphoSitePlus
S615 Phosphorylation PhosphoSitePlus
R616 Methylation PhosphoSitePlus
R619 Methylation PhosphoSitePlus
Y625 Phosphorylation UniProt 31439799
R626 Methylation PhosphoSitePlus   UniProt 24129315
R633 Methylation PhosphoSitePlus   UniProt 24129315
Y636 Phosphorylation PhosphoSitePlus   UniProt 31439799
Y639 Phosphorylation UniProt 31439799
R640 Methylation PhosphoSitePlus   UniProt 24129315
S642 Phosphorylation PhosphoSitePlus
S644 O-Glycosylation GlyGen   UniProt 34074792
T646 Phosphorylation PhosphoSitePlus
S649 O-Glycosylation GlyGen   UniProt 34074792
Y651 Phosphorylation PhosphoSitePlus   UniProt 31439799
T652 Phosphorylation PhosphoSitePlus
S657 Phosphorylation PhosphoSitePlus
Y662 Phosphorylation PhosphoSitePlus   UniProt 31439799
S663 Phosphorylation PhosphoSitePlus
Y665 Phosphorylation PhosphoSitePlus   UniProt 31439799
R667 Methylation PhosphoSitePlus
Y670 Phosphorylation PhosphoSitePlus   UniProt 31439799
K675 Methylation PhosphoSitePlus
R676 Methylation IEDB 28649982
S681 Phosphorylation PhosphoSitePlus
R684 Methylation PhosphoSitePlus
R688 Methylation PhosphoSitePlus
R690 Methylation PhosphoSitePlus
R695 Methylation PhosphoSitePlus
R698 Methylation PhosphoSitePlus   UniProt 24129315
Site PTM Type PTM Enzyme Score Source PMID
S6 Phosphorylation HPRD 19651622
S8 Phosphorylation HPRD 19651622, 20068231
S10 Phosphorylation HPRD 20068231
S12 Phosphorylation HPRD 20068231
S23 Phosphorylation HPRD 20068231
S24 Phosphorylation HPRD 20068231
S26 Phosphorylation HPRD 20068231
S39 Phosphorylation HPRD 20068231
T51 Phosphorylation HPRD 20068231
S115 Phosphorylation HPRD 20068231
S120 Phosphorylation HPRD 19651622
S307 Phosphorylation HPRD 20068231
S335 Phosphorylation HPRD 18669648, 20068231
S343 Phosphorylation HPRD 20068231
T345 Phosphorylation HPRD 18669648, 20068231
S611 Phosphorylation HPRD 17924679
S615 Phosphorylation HPRD 17924679
S681 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S6 Phosphorylation HPRD 19651622
S8 Phosphorylation HPRD 19651622, 20068231
S10 Phosphorylation HPRD 20068231
S12 Phosphorylation HPRD 20068231
S23 Phosphorylation HPRD 20068231
S24 Phosphorylation HPRD 20068231
S26 Phosphorylation HPRD 20068231
S39 Phosphorylation HPRD 20068231
T51 Phosphorylation HPRD 20068231
S115 Phosphorylation HPRD 20068231
S120 Phosphorylation HPRD 19651622
S307 Phosphorylation HPRD 20068231
S335 Phosphorylation HPRD 18669648, 20068231
S343 Phosphorylation HPRD 20068231
T345 Phosphorylation HPRD 18669648, 20068231
S611 Phosphorylation HPRD 17924679
S615 Phosphorylation HPRD 17924679
S681 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S12 C12 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S12 G12 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S12 R12 Biomuta DOID:1324 / lung cancer [ cosmic ]
K63 R63 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y78 C78 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
R81 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R81 Q81 Biomuta DOID:363 / uterine cancer [ icgc ]
S97 A97 Biomuta DOID:1324 / lung cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] DOID:363 / uterine cancer [ cosmic, icgc ] DOID:5041 / esophageal cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic, icgc, cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ]
S115 R115 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K125 N125 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K128 Q128 Biomuta DOID:1319 / brain cancer [ icgc ]
S264 L264 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T292 P292 Biomuta DOID:5158 / pleural cancer [ cosmic ]
Y294 * Biomuta DOID:4159 / skin cancer [ cosmic ]
S343 F343 Biomuta DOID:4159 / skin cancer [ cosmic ]
S436 L436 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T478 P478 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S482 A482 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S483 F483 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R599 H599 Biomuta DOID:363 / uterine cancer [ icgc ]
R608 H608 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
R608 G608 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
R612 C612 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
R612 H612 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R616 H616 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R626 W626 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R626 Q626 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y636 C636 Biomuta DOID:4159 / skin cancer [ cosmic ]
R640 P640 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R640 C640 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ]
R640 H640 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S644 C644 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S649 N649 Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y651 F651 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
R667 W667 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
R667 G667 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y670 * Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
K675 T675 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R676 Q676 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
R684 W684 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R688 Q688 Biomuta DOID:4159 / skin cancer [ cosmic ]
R690 C690 Biomuta DOID:9256 / colorectal cancer [ cosmic ]