Protein Information

Cytoscape View

UniProt AC / UniProt ID Q14332 / FZD2_HUMAN
Protein Name Frizzled-2 precursor
Gene Name Name: FZD2
Organism Homo sapiens (Human)

PRO ID PR:Q14332
DAG View
PRO Name frizzled-2 (human)
Definition A frizzled-2 that is encoded in the genome of human.
Short Label hFZD2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q14332 (FZD2) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S32 O-Glycosylation PhosphoSitePlus
K127 Ubiquitination PhosphoSitePlus
T165 O-Glycosylation PhosphoSitePlus
T166 O-Glycosylation PhosphoSitePlus
T179 O-Glycosylation PhosphoSitePlus
T194 O-Glycosylation PhosphoSitePlus
K206 Ubiquitination PhosphoSitePlus
K214 Ubiquitination PhosphoSitePlus
K446 Methylation PhosphoSitePlus
T534 Phosphorylation PhosphoSitePlus
S541 Phosphorylation PhosphoSitePlus
S547 Phosphorylation PhosphoSitePlus
Y552 Phosphorylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K206 * Biomuta DOID:1324 / lung cancer [ tcga ]
K446 N446 Biomuta DOID:3070 / malignant glioma [ tcga ]
S541 L541 Biomuta DOID:0070003 / blastoma [ cosmic ]