iPTMnet Report for Q14332 (FZD2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14332 / FZD2_HUMAN
Protein Name Frizzled-2 precursor
Gene Name Name: FZD2
Organism Homo sapiens (Human)

PRO ID PR:Q14332
DAG View
PRO Name frizzled-2 (human)
Definition A frizzled-2 that is encoded in the genome of human.
Short Label hFZD2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14332 (FZD2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S32 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
N53 N-Glycosylation GlyGen   UniProt 29748286
K127 Ubiquitination PhosphoSitePlus
T165 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171
T166 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T179 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171
T194 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
K206 Ubiquitination PhosphoSitePlus
K214 Ubiquitination PhosphoSitePlus
K446 Methylation PhosphoSitePlus
T534 Phosphorylation PhosphoSitePlus
S541 Phosphorylation PhosphoSitePlus
S547 Phosphorylation PhosphoSitePlus
Y552 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K206 Q206 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K446 N446 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S541 L541 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]