iPTMnet Report for Q14324 (MYBPC2)
Protein Information
| UniProt AC / UniProt ID | Q14324 / MYPC2_HUMAN |
| Protein Name | Myosin-binding protein C, fast-type |
| Gene Name | Name: MYBPC2 Synonyms:MYBPCF; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q14324 |
| PRO Name | myosin-binding protein C, fast-type (human) |
| Definition | A myosin-binding protein C, fast-type that is encoded in the genome of human. |
| Short Label | hMYBPC2 |
| Category | organism-gene |
Q14324 (MYBPC2) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S44 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T46 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S98 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S105 | Phosphorylation | score0 | HPRD | 17081983 | ||
| K223 | Acetylation | score1 | PhosphoSitePlus | |||
| K228 | Acetylation | score1 | PhosphoSitePlus | |||
| K249 | Acetylation | score1 | PhosphoSitePlus | |||
| S409 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y472 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S481 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S722 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S820 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T849 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S962 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y967 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y1003 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y1007 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1015 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K1078 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K1085 | Methylation | score1 | PhosphoSitePlus | |||
| Y1099 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1104 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T46 | S46 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| K228 | E228 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| S722 | F722 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S820 | R820 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] |
DAG View