Protein Information

Cytoscape View

UniProt AC / UniProt ID Q14318 / FKBP8_HUMAN
Protein Name Peptidyl-prolyl cis-trans isomerase FKBP8
Gene Name Name: FKBP8
Organism Homo sapiens (Human)

PRO ID PR:Q14318
DAG View
PRO Name peptidyl-prolyl cis-trans isomerase FKBP8 (human)
Definition A peptidyl-prolyl cis-trans isomerase FKBP8 that is encoded in the genome of human.
Short Label hFKBP8
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q14318 (FKBP8) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
Ubiquitination PRO
K105 Ubiquitination PhosphoSitePlus
T106 Phosphorylation PhosphoSitePlus
Y232 Phosphorylation PhosphoSitePlus
K249 Ubiquitination PhosphoSitePlus   UniProt 25621951
K271 Methylation PhosphoSitePlus
K271 Ubiquitination PhosphoSitePlus   UniProt 25621951
K273 Ubiquitination PhosphoSitePlus   UniProt 25621951
S281 Phosphorylation PhosphoSitePlus
K284 Ubiquitination PhosphoSitePlus   UniProt 25621951
Y288 Phosphorylation PhosphoSitePlus
C295 S-Nitrosylation dbSNO 26338901
S296 Phosphorylation PhosphoSitePlus   UniProt 23186163
K307 Ubiquitination PhosphoSitePlus   UniProt 25621951
K314 Ubiquitination PhosphoSitePlus   UniProt 25621951
Y322 Phosphorylation PhosphoSitePlus
S323 Phosphorylation PhosphoSitePlus
K334 Ubiquitination PhosphoSitePlus   UniProt 25621951
K340 Ubiquitination PhosphoSitePlus   UniProt 25621951
T341 Phosphorylation PhosphoSitePlus
S347 Phosphorylation PhosphoSitePlus
K348 Acetylation PhosphoSitePlus
K348 Ubiquitination PhosphoSitePlus   UniProt 25621951
K351 Ubiquitination UniProt 25621951
K352 Ubiquitination UniProt 25621951
S358 Phosphorylation PhosphoSitePlus
Y364 Phosphorylation PhosphoSitePlus
K366 Ubiquitination PhosphoSitePlus
K377 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y323 Phosphorylation HPRD 15592455


PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000047423 (hFKBP8/UbiqLys+) ub PRO

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T106 M106 Biomuta DOID:9256 / colorectal cancer [ tcga ]
T106 A106 Biomuta DOID:1909 / melanoma [ cosmic ]
S281 L281 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:1909 / melanoma [ cosmic ]
K284 R284 Biomuta DOID:4362 / cervical cancer [ cosmic ]
Y288 * Biomuta DOID:3571 / liver cancer [ icgc ]
T341 M341 Biomuta DOID:3070 / malignant glioma [ cosmic ]