iPTMnet Report for Q14242 (SELPLG)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14242 / SELPL_HUMAN
Protein Name P-selectin glycoprotein ligand 1 precursor
Gene Name Name: SELPLG
Organism Homo sapiens (Human)

PRO ID PR:Q14242
DAG View
PRO Name P-selectin glycoprotein ligand 1 (human)
Definition A P-selectin glycoprotein ligand 1 that is encoded in the genome of human.
Short Label hSELPLG
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14242 (SELPLG) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T57 O-Glycosylation GlyGen   UniProt 11081633, 17868453
T67 Phosphorylation PhosphoSitePlus
T69 Phosphorylation PhosphoSitePlus
T73 Phosphorylation PhosphoSitePlus
T81 Phosphorylation PhosphoSitePlus
T82 Phosphorylation PhosphoSitePlus
T123 O-Glycosylation GlyGen 25813380
T124 O-Glycosylation GlyGen 25813380
T129 O-Glycosylation GlyGen 25813380
T157 Phosphorylation PhosphoSitePlus
T159 Phosphorylation PhosphoSitePlus
S287 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S289 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S290 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T292 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
Y357 Phosphorylation PhosphoSitePlus
S358 Phosphorylation PhosphoSitePlus
K388 Ubiquitination PhosphoSitePlus
S389 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T393 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T406 Phosphorylation PhosphoSitePlus   UniProt 23186163
S409 Phosphorylation PhosphoSitePlus   UniProt 23186163


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T57 M57 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T129 M129 Biomuta DOID:1324 / lung cancer [ cosmic ]
T157 M157 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
S287 C287 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S287 F287 Biomuta DOID:4159 / skin cancer [ cosmic ]
S289 F289 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S290 Y290 Biomuta DOID:4362 / cervical cancer [ icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S290 F290 Biomuta DOID:4159 / skin cancer [ cosmic ]
S389 R389 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T393 M393 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S409 C409 Biomuta DOID:1324 / lung cancer [ cosmic ]
S409 I409 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S409 N409 Biomuta DOID:9256 / colorectal cancer [ cosmic ]