iPTMnet Report for Q14203 (DCTN1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14203 / DCTN1_HUMAN
Protein Name Dynactin subunit 1
Gene Name Name: DCTN1
Organism Homo sapiens (Human)

PRO ID PR:Q14203
DAG View
PRO Name dynactin subunit 1 (human)
Definition A dynactin subunit 1 that is encoded in the genome of human.
Short Label hDCTN1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14203 (DCTN1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R17 Methylation PhosphoSitePlus
S19 Phosphorylation O14965 (AURKA) PhosphoSitePlus 23547029
S23 Phosphorylation PhosphoSitePlus
R25 Methylation PhosphoSitePlus
S31 Phosphorylation PhosphoSitePlus
C81 Methylation IEDB 31844290
S105 Phosphorylation phospho.ELM   PhosphoSitePlus 22067460
T108 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 22067460, 18669648, 19690332
S111 Phosphorylation PhosphoSitePlus
K115 Ubiquitination PhosphoSitePlus
T122 Phosphorylation PhosphoSitePlus
T145 Phosphorylation UniProt 23985322
T146 Phosphorylation UniProt 23985322
T147 Phosphorylation UniProt 23985322
T158 Phosphorylation PhosphoSitePlus
S164 Phosphorylation PhosphoSitePlus
S172 Phosphorylation PhosphoSitePlus
S179 Phosphorylation P53350 (PLK1) PhosphoSitePlus   Signor   UniProt 20679239
S203 Phosphorylation phospho.ELM   PhosphoSitePlus 22067460
S212 Phosphorylation P06493 (CDK1) phospho.ELM   PhosphoSitePlus   UniProt 22067460, 20679239
S214 Phosphorylation phospho.ELM   PhosphoSitePlus 22067460
K230 Acetylation PhosphoSitePlus
K230 Ubiquitination PhosphoSitePlus
T233 Phosphorylation PhosphoSitePlus
K290 Acetylation PhosphoSitePlus
S320 Phosphorylation PhosphoSitePlus
K329 Ubiquitination PhosphoSitePlus
T336 Phosphorylation PhosphoSitePlus
T337 Phosphorylation PhosphoSitePlus
S351 Phosphorylation PhosphoSitePlus
K371 Ubiquitination PhosphoSitePlus
S417 Phosphorylation PhosphoSitePlus
K453 Ubiquitination PhosphoSitePlus
K501 Ubiquitination PhosphoSitePlus
Y513 Phosphorylation PhosphoSitePlus
K518 Ubiquitination PhosphoSitePlus
S541 Phosphorylation phospho.ELM   PhosphoSitePlus 22067460
K556 Ubiquitination PhosphoSitePlus
K558 Ubiquitination PhosphoSitePlus
K563 Ubiquitination PhosphoSitePlus
K567 Ubiquitination PhosphoSitePlus
C605 Methylation IEDB 31844290
C617 Methylation IEDB 31844290
K618 Ubiquitination PhosphoSitePlus
K629 Ubiquitination PhosphoSitePlus
S637 Phosphorylation PhosphoSitePlus
S687 Phosphorylation PhosphoSitePlus
S693 Phosphorylation PhosphoSitePlus
K722 Ubiquitination PhosphoSitePlus
K920 Ubiquitination PhosphoSitePlus
T936 Phosphorylation PhosphoSitePlus
K962 Ubiquitination PhosphoSitePlus
K978 Ubiquitination PhosphoSitePlus
S982 Phosphorylation PhosphoSitePlus
K993 Ubiquitination PhosphoSitePlus
T996 Phosphorylation PhosphoSitePlus
T1001 Phosphorylation PhosphoSitePlus
S1041 Phosphorylation PhosphoSitePlus
K1115 Ubiquitination PhosphoSitePlus
K1120 Ubiquitination PhosphoSitePlus
K1133 Ubiquitination PhosphoSitePlus
Y1149 Phosphorylation PhosphoSitePlus
K1151 Ubiquitination PhosphoSitePlus
T1152 Phosphorylation PhosphoSitePlus
S1153 Phosphorylation PhosphoSitePlus
K1179 Ubiquitination PhosphoSitePlus
S1180 Phosphorylation PhosphoSitePlus
S1182 Phosphorylation PhosphoSitePlus
K1193 Ubiquitination PhosphoSitePlus
K1201 Ubiquitination PhosphoSitePlus
K1203 Ubiquitination PhosphoSitePlus
K1208 Ubiquitination PhosphoSitePlus
K1235 Ubiquitination PhosphoSitePlus
Y1244 Phosphorylation PhosphoSitePlus
S1251 O-Glycosylation GlyGen 32119511, 34019948, 28510447, ...34725712, 28657654
Site PTM Type PTM Enzyme Score Source PMID
T108 Phosphorylation HPRD 18669648, 19691289, 20068231
S637 Phosphorylation HPRD 18452278
T996 Phosphorylation HPRD 17322306
Site PTM Type PTM Enzyme Score Source PMID
S503 Phosphorylation HPRD 18452278
T862 Phosphorylation HPRD 17322306
Site PTM Type PTM Enzyme Score Source PMID
T116 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T134 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T108 I108 Biomuta DOID:1324 / lung cancer [ cosmic ]
T116 K116 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S1153 I1153 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]