iPTMnet Report for Q14192 (FHL2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14192 / FHL2_HUMAN
Protein Name Four and a half LIM domains protein 2
Gene Name Name: FHL2
Synonyms:DRAL,SLIM3;
Organism Homo sapiens (Human)

PRO ID PR:Q14192
DAG View
PRO Name four and a half LIM domains protein 2 (human)
Definition A four and a half LIM domains protein 2 that is encoded in the genome of human.
Short Label hFHL2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14192 (FHL2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S13 Phosphorylation PhosphoSitePlus
K17 Ubiquitination PhosphoSitePlus
Y27 Phosphorylation PhosphoSitePlus
Y56 Phosphorylation PhosphoSitePlus
K57 Acetylation PhosphoSitePlus
S74 Phosphorylation PhosphoSitePlus
K78 Sumoylation PhosphoSitePlus
K78 Ubiquitination PhosphoSitePlus
Y93 Phosphorylation PhosphoSitePlus
Y97 Phosphorylation PhosphoSitePlus
K100 Ubiquitination PhosphoSitePlus
K106 Ubiquitination PhosphoSitePlus
T107 Phosphorylation PhosphoSitePlus
T112 Phosphorylation PhosphoSitePlus
K118 Sumoylation PhosphoSitePlus
T138 Phosphorylation PhosphoSitePlus
K139 Sumoylation PhosphoSitePlus
K139 Ubiquitination PhosphoSitePlus
S140 Phosphorylation PhosphoSitePlus
K144 Sumoylation PhosphoSitePlus
K144 Ubiquitination PhosphoSitePlus
Y154 Phosphorylation PhosphoSitePlus
K156 Ubiquitination PhosphoSitePlus
K166 Ubiquitination PhosphoSitePlus
K167 Sumoylation PhosphoSitePlus
K167 Ubiquitination PhosphoSitePlus
T175 Phosphorylation PhosphoSitePlus
Y176 Phosphorylation PhosphoSitePlus
T189 Phosphorylation PhosphoSitePlus
C209 Methylation IEDB 31844290
Y217 Phosphorylation PhosphoSitePlus
K220 Sumoylation PhosphoSitePlus
K220 Ubiquitination PhosphoSitePlus
K235 Ubiquitination PhosphoSitePlus
Y236 Phosphorylation PhosphoSitePlus
S238 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
K252 Ubiquitination PhosphoSitePlus
K253 Sumoylation PhosphoSitePlus
K253 Ubiquitination PhosphoSitePlus
S255 Phosphorylation PhosphoSitePlus
K277 Acetylation PhosphoSitePlus
K277 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T171 Phosphorylation HPRD 20068231
S238 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y97 * Biomuta DOID:10283 / prostate cancer [ cosmic ]
K167 N167 Biomuta DOID:363 / uterine cancer [ icgc ]
T171 M171 Biomuta DOID:363 / uterine cancer [ cosmic ]
S238 F238 Biomuta DOID:10534 / stomach cancer [ cosmic ]