Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14190 / SIM2_HUMAN
Protein Name Single-minded homolog 2
Gene Name Name: SIM2
Synonyms:BHLHE15;
Organism Homo sapiens (Human)

PRO ID PR:Q14190
DAG View
PRO Name single-minded homolog 2 (human)
Definition A single-minded homolog 2 that is encoded in the genome of human.
Short Label hSIM2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14190 (SIM2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S31 Phosphorylation PhosphoSitePlus
T34 Phosphorylation PhosphoSitePlus
S35 Phosphorylation PhosphoSitePlus
S115 Phosphorylation PhosphoSitePlus
Y188 Phosphorylation PhosphoSitePlus
Y228 Phosphorylation PhosphoSitePlus
S229 Phosphorylation PhosphoSitePlus
S237 Phosphorylation PhosphoSitePlus
S343 Phosphorylation PhosphoSitePlus
T366 Phosphorylation PhosphoSitePlus
S471 Phosphorylation PhosphoSitePlus
T585 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y228 C228 Biomuta DOID:363 / uterine cancer [ tcga ]
S237 G237 Biomuta DOID:1793 / pancreatic cancer [ tcga ]
S343 Y343 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]