iPTMnet Report for Q14190 (SIM2)
Protein Information
UniProt AC / UniProt ID | Q14190 / SIM2_HUMAN |
Protein Name | Single-minded homolog 2 |
Gene Name | Name: SIM2 Synonyms:BHLHE15; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q14190 |
PRO Name | single-minded homolog 2 (human) |
Definition | A single-minded homolog 2 that is encoded in the genome of human. |
Short Label | hSIM2 |
Category | organism-gene |
Q14190 (SIM2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S31 | Phosphorylation | score1 | PhosphoSitePlus | |||
T34 | Phosphorylation | score1 | PhosphoSitePlus | |||
S35 | Phosphorylation | score1 | PhosphoSitePlus | |||
S115 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y188 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y228 | Phosphorylation | score1 | PhosphoSitePlus | |||
S229 | Phosphorylation | score1 | PhosphoSitePlus | |||
S237 | Phosphorylation | score1 | PhosphoSitePlus | |||
S343 | Phosphorylation | score1 | PhosphoSitePlus | |||
T366 | Phosphorylation | score1 | PhosphoSitePlus | |||
S471 | Phosphorylation | score1 | PhosphoSitePlus | |||
T585 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S115 | F115 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
Y228 | C228 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
S237 | G237 | Biomuta | DOID:10283 / prostate cancer [ cosmic, icgc ] | |
S343 | Y343 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |