iPTMnet Report for Q14190 (SIM2)
Protein Information
| UniProt AC / UniProt ID | Q14190 / SIM2_HUMAN |
| Protein Name | Single-minded homolog 2 |
| Gene Name | Name: SIM2 Synonyms:BHLHE15; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q14190 |
| PRO Name | single-minded homolog 2 (human) |
| Definition | A single-minded homolog 2 that is encoded in the genome of human. |
| Short Label | hSIM2 |
| Category | organism-gene |
Q14190 (SIM2) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S31 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T34 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S35 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S115 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y188 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y228 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S229 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S237 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S343 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T366 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S471 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T585 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S115 | F115 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| Y228 | C228 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| S237 | G237 | Biomuta | DOID:10283 / prostate cancer [ cosmic, icgc ] | |
| S343 | Y343 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |
DAG View