Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14183 / DOC2A_HUMAN
Protein Name Double C2-like domain-containing protein alpha
Gene Name Name: DOC2A
Organism Homo sapiens (Human)

PRO ID PR:Q14183
DAG View
PRO Name double C2-like domain-containing protein alpha (human)
Definition A double C2-like domain-containing protein alpha that is encoded in the genome of human.
Short Label hDOC2A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14183 (DOC2A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K139 Ubiquitination PhosphoSitePlus
T171 Phosphorylation PhosphoSitePlus
S221 Phosphorylation PhosphoSitePlus
Y294 Phosphorylation PhosphoSitePlus
T313 Phosphorylation PhosphoSitePlus
S329 Phosphorylation PhosphoSitePlus
T333 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T171 K171 Biomuta DOID:3571 / liver cancer [ icgc ]
S329 P329 Biomuta DOID:363 / uterine cancer [ tcga ]
T333 A333 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ]