iPTMnet Report for Q14151 (SAFB2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14151 / SAFB2_HUMAN
Protein Name Scaffold attachment factor B2
Gene Name Name: SAFB2
Synonyms:KIAA0138;
Organism Homo sapiens (Human)

PRO ID PR:Q14151
DAG View
PRO Name scaffold attachment factor B2 (human)
Definition A scaffold attachment factor B2 that is encoded in the genome of human.
Short Label hSAFB2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14151 (SAFB2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22814378, 22223895
T4 Phosphorylation PhosphoSitePlus
S8 Phosphorylation PhosphoSitePlus
S11 Phosphorylation PhosphoSitePlus
S17 Phosphorylation PhosphoSitePlus
S31 Phosphorylation PhosphoSitePlus
T49 Phosphorylation PhosphoSitePlus
S54 Phosphorylation PhosphoSitePlus   UniProt 23186163
R59 Methylation PhosphoSitePlus
K65 Sumoylation PhosphoSitePlus
T81 Phosphorylation IEDB 35494241
S85 Phosphorylation PhosphoSitePlus
K94 Sumoylation PhosphoSitePlus
T100 Phosphorylation PhosphoSitePlus
S109 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983, 15302935, ...19367720, 20068231
S158 Phosphorylation PhosphoSitePlus   UniProt 24275569
Y165 Phosphorylation PhosphoSitePlus
K188 Ubiquitination PhosphoSitePlus
S194 Phosphorylation PhosphoSitePlus
S195 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 15302935
K199 Ubiquitination PhosphoSitePlus
T201 Phosphorylation PhosphoSitePlus   UniProt 20068231
S207 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17287340, 15302935, 18669648, ...23186163, 20068231
K215 Ubiquitination PhosphoSitePlus
C224 S-Nitrosylation dbSNO 26338901, 22178444
K225 Methylation PhosphoSitePlus
K225 Sumoylation PhosphoSitePlus
K225 Ubiquitination PhosphoSitePlus
S226 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K230 Sumoylation PhosphoSitePlus
K230 Ubiquitination PhosphoSitePlus
S233 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S234 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T244 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S245 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S246 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K252 Sumoylation PhosphoSitePlus
S262 Phosphorylation PhosphoSitePlus
S274 Phosphorylation PhosphoSitePlus
K284 Ubiquitination PhosphoSitePlus
S287 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K293 Acetylation PhosphoSitePlus
K293 Sumoylation PhosphoSitePlus
K293 Ubiquitination PhosphoSitePlus
S320 Phosphorylation PhosphoSitePlus
S321 Phosphorylation PhosphoSitePlus
S330 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S331 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T339 Phosphorylation PhosphoSitePlus
S343 Phosphorylation P28482 (MAPK1) neXtProt   phospho.ELM   PhosphoSitePlus 18669648, 22028470, 18220336
S349 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K355 Acetylation PhosphoSitePlus
K355 Ubiquitination PhosphoSitePlus
K369 Ubiquitination PhosphoSitePlus
K380 Sumoylation PhosphoSitePlus
K380 Ubiquitination PhosphoSitePlus
K385 Sumoylation PhosphoSitePlus
K388 Acetylation PhosphoSitePlus
K388 Sumoylation PhosphoSitePlus
K391 Acetylation PhosphoSitePlus
K391 Sumoylation PhosphoSitePlus
K395 Sumoylation PhosphoSitePlus
K424 Acetylation PhosphoSitePlus
K424 Ubiquitination PhosphoSitePlus
K429 Acetylation PhosphoSitePlus
K429 Ubiquitination PhosphoSitePlus
K432 Ubiquitination PhosphoSitePlus
K437 Acetylation PhosphoSitePlus
K437 Ubiquitination PhosphoSitePlus
T440 Phosphorylation PhosphoSitePlus
S444 Phosphorylation PhosphoSitePlus
K463 Acetylation PhosphoSitePlus
T471 Phosphorylation PhosphoSitePlus
S479 Phosphorylation PhosphoSitePlus
K501 Sumoylation PhosphoSitePlus
S506 Phosphorylation PhosphoSitePlus
S507 Phosphorylation PhosphoSitePlus   UniProt 23186163
S513 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 20068231
K517 Sumoylation PhosphoSitePlus
K524 Sumoylation PhosphoSitePlus
K528 Acetylation PhosphoSitePlus
K531 Ubiquitination PhosphoSitePlus
K532 Acetylation PhosphoSitePlus
K532 Ubiquitination PhosphoSitePlus
K541 Sumoylation PhosphoSitePlus
K551 Sumoylation PhosphoSitePlus
K551 Ubiquitination PhosphoSitePlus
S563 Phosphorylation PhosphoSitePlus
S565 Phosphorylation PhosphoSitePlus
K576 Acetylation PhosphoSitePlus
S577 O-Glycosylation GlyGen 23301498, 30379171, 34019948, ...35083852
K578 Ubiquitination PhosphoSitePlus
K586 Ubiquitination PhosphoSitePlus
T588 Phosphorylation PhosphoSitePlus
S591 Phosphorylation PhosphoSitePlus
S613 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K616 Acetylation PhosphoSitePlus   UniProt 19608861
K616 Ubiquitination PhosphoSitePlus
R730 Methylation PhosphoSitePlus
Y732 Phosphorylation PhosphoSitePlus
Y741 Phosphorylation PhosphoSitePlus
R753 Methylation PhosphoSitePlus
Y754 Phosphorylation PhosphoSitePlus
R773 Methylation PhosphoSitePlus
Y776 Phosphorylation PhosphoSitePlus
S787 Phosphorylation PhosphoSitePlus   UniProt 23186163
S818 Phosphorylation PhosphoSitePlus
Y825 Phosphorylation PhosphoSitePlus
S827 Phosphorylation PhosphoSitePlus
K829 Acetylation PhosphoSitePlus
K829 Methylation PhosphoSitePlus
S832 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983
R835 Methylation PhosphoSitePlus
R842 Methylation PhosphoSitePlus
R845 Methylation PhosphoSitePlus
R883 Methylation PhosphoSitePlus
S886 Phosphorylation PhosphoSitePlus   UniProt 23186163
R897 Methylation PhosphoSitePlus   UniProt 24129315
R903 Methylation PhosphoSitePlus   UniProt 24129315
R932 Methylation PhosphoSitePlus
R935 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T4 Phosphorylation HPRD 18491316
S8 Phosphorylation HPRD 18491316, 20068231
S31 Phosphorylation HPRD 17924679
S54 Phosphorylation HPRD 20068231
S109 Phosphorylation HPRD 19651622, 15302935, 20068231, ...18452278
S194 Phosphorylation HPRD 19664995, 20068231
S195 Phosphorylation HPRD 19413330, 18669648, 15302935, ...20068231
T201 Phosphorylation HPRD 19413330, 20068231
S207 Phosphorylation HPRD 15302935, 18669648, 17287340, ...20068231
S226 Phosphorylation HPRD 18669648
S233 Phosphorylation HPRD 19651622, 18669648, 20068231, ...18452278
S234 Phosphorylation HPRD 19651622, 18669648, 18452278
T244 Phosphorylation HPRD 20166139, 18669648, 20068231
S245 Phosphorylation HPRD 18669648, 20068231, 18452278
S246 Phosphorylation HPRD 19651622, 18669648, 20068231, ...18452278
S287 Phosphorylation HPRD 19651622, 18669648, 20068231
S330 Phosphorylation HPRD 18669648, 18452278
S331 Phosphorylation HPRD 18669648, 20068231, 18452278
S343 Phosphorylation HPRD 19664995, 18452278, 18669648, ...15345747, 19415658, 20068231
S349 Phosphorylation HPRD 18669648
S444 Phosphorylation HPRD 20068231
S506 Phosphorylation HPRD 20068231
S513 Phosphorylation HPRD 17081983, 20068231
S613 Phosphorylation HPRD 18669648, 20068231
S832 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 V2 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S85 L85 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S158 F158 Biomuta DOID:4159 / skin cancer [ cosmic ]
K188 N188 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S207 F207 Biomuta DOID:4159 / skin cancer [ cosmic ]
S207 Y207 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K385 Q385 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K388 N388 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K391 N391 Biomuta DOID:1324 / lung cancer [ cosmic ]
K501 R501 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:263 / kidney cancer [ cosmic ]
S513 F513 Biomuta DOID:4159 / skin cancer [ cosmic ]
K528 N528 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
K551 R551 Biomuta DOID:363 / uterine cancer [ icgc ]
K576 T576 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S577 L577 Biomuta DOID:4159 / skin cancer [ cosmic ]
K586 Q586 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S591 F591 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S613 L613 Biomuta DOID:1319 / brain cancer [ cosmic ]
Y741 C741 Biomuta DOID:4159 / skin cancer [ cosmic ]
R773 W773 Biomuta [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
S787 L787 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic, icgc ]
K829 * Biomuta DOID:2531 / hematologic cancer [ cosmic ]
R835 Q835 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R835 W835 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:363 / uterine cancer [ cosmic, icgc ] DOID:5041 / esophageal cancer [ cosmic, icgc ]
R845 C845 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R845 S845 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
R903 Q903 Biomuta DOID:4159 / skin cancer [ cosmic ]
R932 Q932 Biomuta DOID:1324 / lung cancer [ cosmic ]