iPTMnet Report for Q14149 (MORC3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14149 / MORC3_HUMAN
Protein Name MORC family CW-type zinc finger protein 3
Gene Name Name: MORC3
Synonyms:KIAA0136;
Organism Homo sapiens (Human)

PRO ID PR:Q14149
DAG View
PRO Name MORC family CW-type zinc finger protein 3 (human)
Definition A MORC family CW-type zinc finger protein 3 that is encoded in the genome of human.
Short Label hMORC3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14149 (MORC3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S12 Phosphorylation PhosphoSitePlus
S82 Phosphorylation PhosphoSitePlus
K105 Ubiquitination PhosphoSitePlus
K152 Ubiquitination PhosphoSitePlus
K191 Ubiquitination PhosphoSitePlus
K205 Sumoylation PhosphoSitePlus
K214 Ubiquitination PhosphoSitePlus
K216 Ubiquitination PhosphoSitePlus
K231 Acetylation PhosphoSitePlus
K231 Ubiquitination PhosphoSitePlus
Y254 Phosphorylation PhosphoSitePlus
Y259 Phosphorylation PhosphoSitePlus
K261 Methylation PhosphoSitePlus
K261 Ubiquitination PhosphoSitePlus
K274 Ubiquitination PhosphoSitePlus
K280 Ubiquitination PhosphoSitePlus
K293 Ubiquitination PhosphoSitePlus
K297 Ubiquitination PhosphoSitePlus
T298 Phosphorylation PhosphoSitePlus
T302 Phosphorylation PhosphoSitePlus
K310 Ubiquitination PhosphoSitePlus
Y313 Phosphorylation PhosphoSitePlus
Y318 Phosphorylation PhosphoSitePlus
K325 Ubiquitination PhosphoSitePlus
K329 Ubiquitination PhosphoSitePlus
K377 Ubiquitination PhosphoSitePlus
K386 Ubiquitination PhosphoSitePlus
K389 Ubiquitination PhosphoSitePlus
K404 Ubiquitination PhosphoSitePlus
K421 Ubiquitination PhosphoSitePlus
K432 Ubiquitination PhosphoSitePlus
Y434 Phosphorylation PhosphoSitePlus
C446 S-Nitrosylation dbSNO 26338901
K464 Ubiquitination PhosphoSitePlus
T494 Phosphorylation PhosphoSitePlus
S497 Phosphorylation PhosphoSitePlus
T498 Phosphorylation PhosphoSitePlus
S500 Phosphorylation PhosphoSitePlus
S502 Phosphorylation HPRD   phospho.ELM 18669648
S503 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648
S514 Phosphorylation PhosphoSitePlus   UniProt 23186163
S540 Phosphorylation PhosphoSitePlus   UniProt 23186163
K542 Ubiquitination PhosphoSitePlus
S546 Phosphorylation PhosphoSitePlus
T547 Phosphorylation PhosphoSitePlus
S549 Phosphorylation PhosphoSitePlus
S550 Phosphorylation PhosphoSitePlus
K555 Ubiquitination PhosphoSitePlus
S560 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19651622, 23186163
S561 O-Glycosylation GlyGen 30379171, 29351928
S561 Phosphorylation PhosphoSitePlus
K597 Sumoylation PhosphoSitePlus
K650 Sumoylation PhosphoSitePlus
K651 Sumoylation PhosphoSitePlus
T681 Phosphorylation PhosphoSitePlus
K687 Ubiquitination PhosphoSitePlus
K710 Ubiquitination PhosphoSitePlus
K737 Acetylation PhosphoSitePlus
K740 Sumoylation PhosphoSitePlus
K762 Ubiquitination PhosphoSitePlus
S763 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S765 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S771 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
Y773 Phosphorylation HPRD 19651622
K785 Ubiquitination PhosphoSitePlus
K794 Sumoylation PhosphoSitePlus
K794 Ubiquitination PhosphoSitePlus
S798 Phosphorylation PhosphoSitePlus
S801 Phosphorylation PhosphoSitePlus
K806 Ubiquitination PhosphoSitePlus
K825 Ubiquitination PhosphoSitePlus
K834 Ubiquitination PhosphoSitePlus
K844 Ubiquitination PhosphoSitePlus
K855 Sumoylation PhosphoSitePlus
K855 Ubiquitination PhosphoSitePlus
K862 Ubiquitination PhosphoSitePlus
S873 Phosphorylation PhosphoSitePlus
K891 Ubiquitination PhosphoSitePlus
S894 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K191 N191 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K214 M214 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y254 C254 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K293 E293 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
Y318 C318 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K421 T421 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
Y434 H434 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S497 L497 Biomuta DOID:363 / uterine cancer [ icgc ]
S497 * Biomuta DOID:3571 / liver cancer [ cosmic ]
S514 L514 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K555 N555 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K555 E555 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S801 F801 Biomuta DOID:4159 / skin cancer [ cosmic ]
K855 N855 Biomuta DOID:4159 / skin cancer [ cosmic ]