iPTMnet Report for Q14147 (DHX34)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14147 / DHX34_HUMAN
Protein Name Probable ATP-dependent RNA helicase DHX34
Gene Name Name: DHX34
Synonyms:DDX34;
Organism Homo sapiens (Human)

PRO ID PR:Q14147
DAG View
PRO Name probable ATP-dependent RNA helicase DHX34 (human)
Definition A probable ATP-dependent RNA helicase DHX34 that is encoded in the genome of human.
Short Label hDHX34
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14147 (DHX34) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S20 Phosphorylation PhosphoSitePlus
K27 Ubiquitination PhosphoSitePlus
K59 Ubiquitination PhosphoSitePlus
T115 Phosphorylation PhosphoSitePlus
R116 Methylation PhosphoSitePlus
R123 Methylation PhosphoSitePlus
K146 Ubiquitination PhosphoSitePlus
S219 Phosphorylation PhosphoSitePlus
K353 Ubiquitination PhosphoSitePlus
S439 Phosphorylation IEDB 35494241
K460 Ubiquitination PhosphoSitePlus
K471 Ubiquitination PhosphoSitePlus
K533 Ubiquitination PhosphoSitePlus
S749 Phosphorylation HPRD   PhosphoSitePlus   UniProt 21406692, 19651622, 18669648, ...24275569, 19690332, 20068231
S750 Phosphorylation HPRD   PhosphoSitePlus   UniProt 21406692, 18452278, 19651622, ...18669648, 24275569, 19690332, 20068231
K772 Ubiquitination PhosphoSitePlus
K774 Acetylation PhosphoSitePlus
K801 Ubiquitination PhosphoSitePlus
K823 Ubiquitination PhosphoSitePlus
K834 Ubiquitination PhosphoSitePlus
S880 Phosphorylation PhosphoSitePlus
S976 Phosphorylation HPRD   PhosphoSitePlus 20068231
K985 Ubiquitination PhosphoSitePlus
T991 Phosphorylation PhosphoSitePlus
S993 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S20 R20 Biomuta DOID:3571 / liver cancer [ cosmic ]
T115 M115 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
R116 W116 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R116 Q116 Biomuta [ cosmic ] DOID:363 / uterine cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
S750 T750 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K774 M774 Biomuta DOID:3571 / liver cancer [ cosmic ]