iPTMnet Report for Q14139 (UBE4A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14139 / UBE4A_HUMAN
Protein Name Ubiquitin conjugation factor E4 A
Gene Name Name: UBE4A
Synonyms:KIAA0126;
Organism Homo sapiens (Human)

PRO ID PR:Q14139
DAG View
PRO Name ubiquitin conjugation factor E4 A (human)
Definition A ubiquitin conjugation factor E4 A that is encoded in the genome of human.
Short Label hUBE4A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14139 (UBE4A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T2 Phosphorylation PhosphoSitePlus
K33 Ubiquitination PhosphoSitePlus
S71 Phosphorylation PhosphoSitePlus
S74 Phosphorylation PhosphoSitePlus
K104 Ubiquitination PhosphoSitePlus
K185 Ubiquitination PhosphoSitePlus
K190 Ubiquitination PhosphoSitePlus
Y313 Phosphorylation PhosphoSitePlus
K317 Ubiquitination PhosphoSitePlus
K386 Acetylation PhosphoSitePlus   UniProt 19608861
K451 Ubiquitination PhosphoSitePlus
Y464 Phosphorylation PhosphoSitePlus
C465 S-Nitrosylation dbSNO 19483679
K468 Ubiquitination PhosphoSitePlus
K478 Ubiquitination PhosphoSitePlus
K487 Ubiquitination PhosphoSitePlus
C490 Methylation IEDB 31844290
K531 Acetylation PhosphoSitePlus
K531 Ubiquitination PhosphoSitePlus
S551 Phosphorylation PhosphoSitePlus
Y749 Phosphorylation PhosphoSitePlus
K766 Ubiquitination PhosphoSitePlus
S773 O-Glycosylation GlyGen 23301498, 36240223
K774 Ubiquitination PhosphoSitePlus
K810 Ubiquitination PhosphoSitePlus
K816 Ubiquitination PhosphoSitePlus
K832 Ubiquitination PhosphoSitePlus
C916 Methylation IEDB 31844290
S940 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S577 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K190 R190 Biomuta DOID:1319 / brain cancer [ cosmic ]
K386 N386 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K468 N468 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K531 E531 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K774 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K816 Q816 Biomuta DOID:9256 / colorectal cancer [ icgc ]