iPTMnet Report for Q14119 (VEZF1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14119 / VEZF1_HUMAN
Protein Name Vascular endothelial zinc finger 1
Gene Name Name: VEZF1
Synonyms:DB1,ZNF161;
Organism Homo sapiens (Human)

PRO ID PR:Q14119
DAG View
PRO Name vascular endothelial zinc finger 1 (human)
Definition A vascular endothelial zinc finger 1 that is encoded in the genome of human.
Short Label hVEZF1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14119 (VEZF1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K41 Sumoylation PhosphoSitePlus
K66 Sumoylation PhosphoSitePlus
S86 Phosphorylation PhosphoSitePlus
K100 Acetylation PhosphoSitePlus
S103 O-Glycosylation GlyGen 27655845, 34846842, 33214551, ...28510447, 35254053, 30397120, 31637018, 34019948, 21740066, 30059200, 35132862, 31492838, 34931806, 20305658, 35289036, 29351928, 28657654, 29237092
T108 O-Glycosylation GlyGen 27655845, 34846842, 33214551, ...28510447, 35254053, 30397120, 31637018, 34019948, 21740066, 30059200, 35132862, 31492838, 34931806, 20305658, 35289036, 29351928, 28657654, 29237092
T110 O-Glycosylation GlyGen 27655845, 34846842, 33214551, ...28510447, 35254053, 30397120, 31637018, 34019948, 21740066, 30059200, 35132862, 31492838, 34931806, 20305658, 35289036, 29351928, 28657654, 29237092
T111 O-Glycosylation GlyGen 27655845, 34846842, 33214551, ...28510447, 35254053, 30397120, 32938750, 34019948, 31637018, 30059200, 35132862, 21740066, 31492838, 34931806, 20305658, 35289036, 29351928, 28657654, 29237092
S117 O-Glycosylation GlyGen 27655845, 34846842, 33214551, ...28510447, 35254053, 30397120, 32938750, 34019948, 31637018, 30059200, 35132862, 21740066, 31492838, 34931806, 20305658, 35289036, 29351928, 28657654, 29237092
T118 O-Glycosylation GlyGen 27655845, 34846842, 33214551, ...28510447, 35254053, 30397120, 32938750, 34019948, 31637018, 30059200, 35132862, 21740066, 31492838, 34931806, 20305658, 35289036, 29351928, 28657654, 29237092
S123 O-Glycosylation GlyGen 27655845, 34846842, 33214551, ...28510447, 35254053, 30397120, 31637018, 34019948, 21740066, 30059200, 35132862, 31492838, 34931806, 20305658, 35289036, 29351928, 28657654, 29237092
S124 O-Glycosylation GlyGen 27655845, 34846842, 33214551, ...28510447, 35254053, 30397120, 31637018, 34019948, 21740066, 30059200, 35132862, 31492838, 34931806, 20305658, 35289036, 29351928, 28657654, 29237092
T126 O-Glycosylation GlyGen 27655845, 34846842, 33214551, ...28510447, 35254053, 30397120, 31637018, 34019948, 21740066, 30059200, 35132862, 31492838, 34931806, 20305658, 35289036, 29351928, 28657654, 29237092
S127 O-Glycosylation GlyGen 27655845, 34846842, 33214551, ...28510447, 35254053, 30397120, 31637018, 34019948, 21740066, 30059200, 35132862, 31492838, 34931806, 20305658, 35289036, 29351928, 28657654, 29237092
S127 Phosphorylation HPRD 20068231
S130 Phosphorylation HPRD 20068231
T131 O-Glycosylation GlyGen 32938750
S137 O-Glycosylation GlyGen 27655845, 34846842, 33214551, ...28510447, 35254053, 30397120, 31637018, 34019948, 21740066, 30059200, 35132862, 31492838, 34931806, 20305658, 35289036, 29351928, 28657654, 29237092
T138 O-Glycosylation GlyGen 27655845, 34846842, 33214551, ...28510447, 35254053, 30397120, 31637018, 34019948, 21740066, 30059200, 35132862, 31492838, 34931806, 20305658, 35289036, 29351928, 28657654, 29237092
T141 O-Glycosylation GlyGen 27655845, 34846842, 33214551, ...28510447, 35254053, 30397120, 31637018, 34019948, 21740066, 30059200, 35132862, 31492838, 34931806, 20305658, 35289036, 29351928, 28657654, 29237092
S142 O-Glycosylation GlyGen 27655845, 34846842, 33214551, ...28510447, 35254053, 30397120, 31637018, 34019948, 21740066, 30059200, 35132862, 31492838, 34931806, 20305658, 35289036, 29351928, 28657654, 29237092
S143 O-Glycosylation GlyGen 27655845, 34846842, 33214551, ...28510447, 35254053, 30397120, 31637018, 34019948, 21740066, 30059200, 35132862, 31492838, 34931806, 20305658, 35289036, 29351928, 28657654, 29237092
S144 O-Glycosylation GlyGen 27655845, 34846842, 33214551, ...28510447, 35254053, 30397120, 31637018, 34019948, 21740066, 30059200, 35132862, 31492838, 34931806, 20305658, 35289036, 29351928, 28657654, 29237092
S144 Phosphorylation HPRD 20068231
T146 O-Glycosylation GlyGen 27655845, 34846842, 33214551, ...28510447, 35254053, 30397120, 31637018, 34019948, 21740066, 30059200, 35132862, 31492838, 34931806, 20305658, 35289036, 29351928, 28657654, 29237092
S149 O-Glycosylation GlyGen 27655845, 34846842, 33214551, ...28510447, 35254053, 30397120, 31637018, 34019948, 21740066, 30059200, 35132862, 31492838, 34931806, 20305658, 35289036, 29351928, 28657654, 29237092
S150 O-Glycosylation GlyGen 27655845, 34846842, 33214551, ...28510447, 35254053, 30397120, 31637018, 34019948, 21740066, 30059200, 35132862, 31492838, 34931806, 20305658, 35289036, 29351928, 28657654, 29237092
S150 Phosphorylation HPRD 20068231
T154 O-Glycosylation GlyGen 27655845, 34846842, 33214551, ...28510447, 35254053, 30397120, 31637018, 34019948, 21740066, 30059200, 35132862, 31492838, 34931806, 20305658, 35289036, 29351928, 28657654, 29237092
T155 Phosphorylation HPRD 20068231
T160 O-Glycosylation GlyGen 27655845, 34846842, 33214551, ...28510447, 35254053, 30397120, 31637018, 34019948, 21740066, 30059200, 35132862, 31492838, 34931806, 20305658, 35289036, 29351928, 28657654, 29237092
K181 Ubiquitination PhosphoSitePlus
S195 Phosphorylation HPRD 20068231
S197 Phosphorylation HPRD   PhosphoSitePlus 19651622, 20068231
K200 Ubiquitination PhosphoSitePlus
C237 Methylation IEDB 31844290
S256 Phosphorylation HPRD   PhosphoSitePlus 20068231
K273 Ubiquitination PhosphoSitePlus
K286 Ubiquitination PhosphoSitePlus
S297 Phosphorylation PhosphoSitePlus
Y300 Phosphorylation PhosphoSitePlus
T302 Phosphorylation HPRD 20068231
S303 Phosphorylation HPRD 20068231
K320 Ubiquitination PhosphoSitePlus
K325 Ubiquitination PhosphoSitePlus
K362 Acetylation PhosphoSitePlus   UniProt 19608861
K362 Ubiquitination PhosphoSitePlus
K375 Ubiquitination PhosphoSitePlus
T517 Phosphorylation HPRD 20068231
S518 Phosphorylation HPRD   PhosphoSitePlus 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K100 T100 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
T108 P108 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T108 N108 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
T111 K111 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S123 I123 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S127 L127 Biomuta DOID:4159 / skin cancer [ cosmic ]
T138 A138 Biomuta DOID:10283 / prostate cancer [ cosmic ]
T155 A155 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K181 T181 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S195 F195 Biomuta DOID:4159 / skin cancer [ cosmic ]
C237 F237 Biomuta DOID:3953 / adrenal gland cancer [ cosmic ]
K286 N286 Biomuta DOID:3571 / liver cancer [ cosmic ]